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Infectious Disease

1171 published articles · Updated continuously

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
mRNA-1283 and BNT162b2 COVID-19 vaccines show protective effectiveness in adults aged 65 and older
Infectious Disease Cohort
mRNA-1283 and BNT162b2 COVID-19 vaccines show protective effectiveness in adults aged 65 and older New Vaccine Cuts Hospital Risk for Seniors by Nearly 60%
This observational cohort study in U.S. adults aged >=65 years found mRNA-1283 had higher adjusted vaccine effectiveness (aVE) for COVID-19…
A new 2025–2026 COVID vaccine slashes hospital risk for seniors by nearly 60%, offering stronger protection when aging immune systems need i…
Randomized trial shows ribavirin increases mutational load and specific transition signatures in HCV
Infectious Disease
Randomized trial shows ribavirin increases mutational load and specific transition signatures in HCV Ribavirin linked to increased hepatitis C virus mutations in trial
This secondary analysis of a randomized trial in HCV-infected participants found ribavirin exposure significantly increased total mutational…
Ribavirin treatment linked to increased hepatitis C virus mutations in a trial, though real-world impact on cure rates remains unclear.
Observational cross-sectional study on environmental covariates and malaria prevalence in Tanzania
Infectious Disease
Observational cross-sectional study on environmental covariates and malaria prevalence in Tanzania Does the grass and shrubs near your home affect malaria risk?
This observational cross-sectional study in Mainland Tanzania examined household-level environmental covariates and malaria parasite prevale…
This matters because where you live can change your family's malaria risk.
Observational cohort study on SARS-CoV-2 evolution in immunocompromised patients
Infectious Disease
Observational cohort study on SARS-CoV-2 evolution in immunocompromised patients Long COVID Virus Changes Shape Inside Severely Ill Patients, Study Finds
This observational cohort study analyzed longitudinal SARS-CoV-2 genomes from 91 immunocompromised patients with COVID-19.
When the virus lingers too long in very sick patients, it changes in unpredictable ways, highlighting the need for stronger treatments.
Modelling analysis review estimates TB cases and deaths averted by screening in ten Asian countries
Infectious Disease
Modelling analysis review estimates TB cases and deaths averted by screening in ten Asian countries A $12 Billion Plan to Save Millions from Tuberculosis
This modelling analysis review evaluates the epidemiological impact and cost implications of scaling up tuberculosis screening across ten hi…
AI scans in communities could save millions of lives by finding silent tuberculosis cases in ten high-risk Asian countries before they sprea…
Observational serological model in Malawi shows rapid SARS-CoV-2 antibody waning and urban-rural differences
Infectious Disease
Observational serological model in Malawi shows rapid SARS-CoV-2 antibody waning and urban-rural differences Malawi Study Rewrites Rules of COVID Immunity
This observational study used serological modelling to reconstruct SARS-CoV-2 infection histories in unvaccinated Malawian adults.
In Malawi, natural immunity fades fast, with antibodies dropping to 5% after one year, so vaccines remain essential for lasting protection.
Selective Decontamination of the Digestive Tract showed no mortality benefit over standard care in mechanically ventilated patients
Infectious Disease RCT
Selective Decontamination of the Digestive Tract showed no mortality benefit over standard care in mechanically ventilated patients A Common ICU Infection Strategy Fails Its Biggest Test
This randomized trial involving 9,289 critically ill patients across 26 ICUs in Australia and Canada evaluated Selective Decontamination of …
A massive ICU trial found that wiping out gut bacteria in ventilated patients reduced infections but did not save more lives.
Adjuvanted RSV vaccine shows efficacy against RSV disease in older adults with comorbidities
Infectious Disease RCT
Adjuvanted RSV vaccine shows efficacy against RSV disease in older adults with comorbidities One RSV Shot Protects High-Risk Older Adults for Three Full Seasons
This post-hoc analysis of a phase 3 trial evaluated an adjuvanted RSVPreF3 dose in medically stable adults aged 60 and older with underlying…
One RSV shot cuts illness risk by 63% to 75% for older adults with COPD, asthma, diabetes, or obesity over three full seasons.
Phase Ia trial of RH5.1 protein with Matrix-M adjuvant in malaria-naive UK adults showed safety and similar immunogenicity across two booster regimens
Infectious Disease Phase II
Phase Ia trial of RH5.1 protein with Matrix-M adjuvant in malaria-naive UK adults showed safety and similar immunogenicity across two booster regimens A Malaria Vaccine Candidate Holds Strong — Even With a Smaller Booster Dose
This Phase Ia clinical trial evaluated the safety and immunogenicity of RH5.1 soluble protein with Matrix-M adjuvant in malaria-naive UK adu…
A malaria vaccine candidate produced strong immune responses even when the final booster dose was cut in half, potentially helping extend va…
Random forest model predicts pediatric varicella encephalitis with excellent performance in a retrospective analysis
Infectious Disease Cohort
Random forest model predicts pediatric varicella encephalitis with excellent performance in a retrospective analysis A Simple Checklist Could Catch the Most Dangerous Chickenpox Complication Early
This retrospective analysis evaluated a random forest model for predicting pediatric varicella encephalitis in 201 children.
A new AI tool predicts dangerous chickenpox brain complications in kids with 95% accuracy using just six simple symptoms like rash duration …
Monoclonal stool antigen test shows high accuracy for H. pylori detection in chronic atrophic gastritis patients
Infectious Disease Cohort
Monoclonal stool antigen test shows high accuracy for H. pylori detection in chronic atrophic gastritis patients A Simple Stool Test Spots a Dangerous Stomach Bug Without a Scope
This prospective primary care study evaluated 287 patients with chronic atrophic gastritis (CAG) using a monoclonal stool antigen test (SAT)…
A simple stool test spots dangerous stomach bugs in people with chronic gastritis, performing even better when the stomach is most at risk.
EBNA1 SeroStrip-HT shows high accuracy for nasopharyngeal carcinoma risk assessment in a nested case-control study
Infectious Disease Cohort
EBNA1 SeroStrip-HT shows high accuracy for nasopharyngeal carcinoma risk assessment in a nested case-control study A Blood Test May Spot a Rare Cancer Years Before Symptoms Appear
This nested case-control study evaluated the EBNA1 SeroStrip-HT in prospective cohorts from Singapore and Shanghai, China.
A simple blood test can spot a rare throat cancer up to four years before symptoms appear, giving doctors time to treat it early.