Metformin, fluvoxamine, or ivermectin for non-hospitalized COVID-19 adults in a Phase 3 trial
Metformin Cuts Long Covid Risk by 40%
This randomized controlled trial in 1323 non-hospitalized adults with SARS-CoV-2 infection evaluated metformin, fluvoxamine, or ivermectin v…
A common diabetes pill taken early in Covid infection cuts the odds of developing long-term symptoms by 40%, offering new hope for millions.
Community-based intervention reduces antibiotic use in Burkina Faso and DRC
New Plan Cuts Dangerous Antibiotic Use in African Villages
In this cluster randomised controlled trial across 44 villages in Burkina Faso and Democratic Republic of Congo, a community-based behaviour…
A simple community plan successfully lowered the use of strong antibiotics in rural Africa.
Systematic review and meta-analysis of Salmonella prevalence and AMR in global wild birds
Wild Birds Are Picking Up Drug-Resistant Germs—And It’s Getting Worse
This systematic review and meta-analysis synthesizes data on Salmonella prevalence and antimicrobial resistance (AMR) patterns across global…
Wild birds are becoming living carriers of drug-resistant bacteria, and that poses a growing risk to human health worldwide.
PPV and voriconazole for endogenous fungal endophthalmitis outbreak improves visual acuity
Contaminated IVs Cause Sudden Blindness in Healthy Adults
This retrospective case series evaluated 26 eyes of 17 immunocompetent patients with endogenous fungal endophthalmitis following a rural cli…
Healthy adults lost vision after contaminated IV infusions, but early surgery and antifungals helped save sight in most cases.
Review Analytical Performance of Multiplex PCR Assays for Tuberculosis and Drug Resistance
New test spots TB and drug resistance in one quick scan
This review evaluates the comprehensive analytical performance of multiplex open real-time PCR assays for tuberculosis and drug resistance i…
A new lab test finds TB and drug resistance in one quick scan, but it misses some rare germs that need more study.
Algorithm development study validates FindPart-w model for identifying SARS-CoV-2 lineage groups in the US
New tool sorts virus variants by how fast they spread
This algorithm development and validation study evaluates the FindPart-w algorithm and constrained RelRe model against the Pango lineage nom…
A new math tool groups virus variants by how fast they spread instead of just looking at their genetic makeup alone.
Cross-sectional review of mass drug administration impact on lymphatic filariasis elimination in Nepal
Mass drug administration reduces lymphatic filariasis in most Nepal districts
This cross-sectional epidemiological monitoring survey review assesses lymphatic filariasis transmission in six endemic districts of Nepal f…
A survey of over 7,000 people in Nepal found that mass drug administration lowered infection rates in most areas, though three sites still n…
Review of preclinical FH12-based Sandwich-ELISA for mucormycosis detection
Lab test shows promise for detecting mucormycosis in humans
This preclinical review evaluates an FH12-based Sandwich-ELISA for detecting mucormycosis. The authors report high specificity for pan-Mucor…
A new lab method detects a specific marker for mucormycosis without cross-reacting with other fungi, offering a potential tool for diagnosis…
Nirmatrelvir-ritonavir showed no reduction in hospitalization or death within 28 days for higher-risk adults in community trials.
New Study Questions Early Use of Paxlovid for Vaccinated Patients
In community-based trials involving higher-risk adults with recent SARS-CoV-2 infection, adding nirmatrelvir-ritonavir to usual care did not…
Getting vaccinated changes how your body fights the virus, and this new research shows that taking Paxlovid early might not be necessary for…
Systematic review and meta-analysis finds higher TB prevalence among people living with HIV in Africa
TB’s Hidden Link: Why HIV Changes the Risk Picture
This systematic review and meta-analysis evaluated bacteriologically-confirmed tuberculosis prevalence in 264,530 people across Southern and…
If you have HIV, your risk of missing a deadly TB diagnosis is far higher—and this study explains why that gap must close now.
Narrative review discusses natural product-based plasmid curing agents versus traditional antibiotic strategies for antimicrobial resistance.
How Natural Plants Could Stop Superbugs Without Killing Them
This narrative review examines the potential of natural product-based plasmid curing agents as an alternative to traditional bactericidal an…
This approach could save antibiotics from becoming useless by forcing superbugs to surrender their defenses rather than fighting them.
Narrative review discusses ecological stability limitations and regulatory challenges in field performance.
Scientists Are Rewriting How Plants Fight Drought and Disease
This narrative review addresses ecological stability limitations, trait trade-offs, and biosafety challenges. The authors note inconsistent …
This research could help grow more food with less water and fewer chemicals by redesigning the tiny organisms that live on plants.