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Infectious Disease

1071 published articles · Updated continuously

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
FMT and SDD show efficacy for CRE decolonisation in meta-analysis of 872 participants
Infectious Disease Meta-analysis
FMT and SDD show efficacy for CRE decolonisation in meta-analysis of 872 participants Can gut bacteria transplants help clear dangerous drug-resistant infections?
A systematic review and meta-analysis of 16 studies with 872 participants found faecal microbiota transplantation (FMT) significantly improv…
Gut bacteria transplants significantly clear dangerous drug-resistant infections, while a targeted antibiotic rinse helps some but may incre…
Nurse-led peer-supported education improves CD4 count and adherence in Thai MSM with HIV
Infectious Disease RCT
Nurse-led peer-supported education improves CD4 count and adherence in Thai MSM with HIV Can group support help men with HIV manage their health better?
A randomized controlled trial of 64 Thai MSM with HIV found that a culturally adapted, nurse-delivered, peer-supported self-management educa…
A supportive group program helped Thai men with HIV improve immune health, stick to their medication, and feel better after just three month…
Acupuncture plus pelvic floor training may improve postpartum urinary incontinence outcomes versus training alone
Infectious Disease Meta-analysis
Acupuncture plus pelvic floor training may improve postpartum urinary incontinence outcomes versus training alone Can acupuncture help new moms with bladder leaks? A review suggests it might
A meta-analysis of 9 RCTs involving 865 women with postpartum urinary incontinence found acupuncture combined with pelvic floor muscle train…
Adding acupuncture to pelvic floor exercises may help new moms with bladder leaks more than exercises alone, though the evidence certainty i…
Meta-analysis finds no benefit of topical antibiotic prophylaxis for endophthalmitis after intravitreal injections
Infectious Disease Meta-analysis
Meta-analysis finds no benefit of topical antibiotic prophylaxis for endophthalmitis after intravitreal injections Do antibiotic eye drops prevent dangerous infections after eye injections?
A systematic review and meta-analysis of over 5.8 million intravitreal injections found no significant difference in endophthalmitis inciden…
A new analysis of nearly 6 million eye injections found that antibiotic drops did not prevent rare infections and may actually increase risk…
Procalcitonin-guided antibiotic protocols reduce therapy duration in critically ill sepsis patients
Infectious Disease Meta-analysis
Procalcitonin-guided antibiotic protocols reduce therapy duration in critically ill sepsis patients Blood test helps guide antibiotic use in sepsis patients, may shorten treatment
A rapid systematic review and meta-analysis of 19 trials (n=6,382) in critically ill adult sepsis patients found procalcitonin-guided antibi…
A blood test that measures procalcitonin may help doctors safely shorten antibiotic treatment for sepsis by about two days.
Meta-analysis finds topical antibiotic prophylaxis does not reduce endophthalmitis after intravitreal injection
Infectious Disease Meta-analysis
Meta-analysis finds topical antibiotic prophylaxis does not reduce endophthalmitis after intravitreal injection Study finds topical antibiotics do not prevent eye infections after injections
A systematic review and meta-analysis of over 3 million intravitreal injections found no significant difference in endophthalmitis incidence…
Topical antibiotic eye drops do not prevent serious eye infections after injections, according to a review of over 3 million procedures.
Short-course antibiotics after appendectomy for complicated appendicitis show similar infection risk to long-course therapy
Infectious Disease Meta-analysis
Short-course antibiotics after appendectomy for complicated appendicitis show similar infection risk to long-course therapy Short-course antibiotics after complicated appendectomy show similar infection risk to longer courses
A meta-analysis of 3251 patients from 4 RCTs and 9 observational studies found short-course antibiotic therapy (<3 days) after appendectomy …
Shorter antibiotics after complicated appendectomy carry similar infection risks to longer courses while often shortening hospital stays.
Linezolid vs clindamycin shows no ICU or hospital stay difference in severe SSTIs
Infectious Disease Meta-analysis
Linezolid vs clindamycin shows no ICU or hospital stay difference in severe SSTIs For severe skin infections, does one antibiotic keep you out of the hospital longer?
A systematic review and meta-analysis of patients with severe or necrotizing skin and soft tissue infections found no significant difference…
For severe skin infections, using linezolid instead of clindamycin does not help patients leave the hospital faster, though it may lower kid…
Meta-analysis finds no mortality difference between CA and CT for drug-resistant P. aeruginosa infections
Infectious Disease Meta-analysis
Meta-analysis finds no mortality difference between CA and CT for drug-resistant P. aeruginosa infections Which antibiotic works better for dangerous drug-resistant infections?
A meta-analysis of 10 observational studies including 1409 patients with drug-resistant P.
Two powerful new antibiotics show equal survival rates for patients fighting dangerous, drug-resistant infections.
Meta-analysis finds no significant difference in outcomes between high- and low-dose ceftriaxone for non-CNS infections
Infectious Disease Meta-analysis
Meta-analysis finds no significant difference in outcomes between high- and low-dose ceftriaxone for non-CNS infections Do higher doses of a common antibiotic help adults with infections?
A meta-analysis of eight studies involving 5145 adults with non-CNS infections found no statistically significant difference in clinical cur…
Higher doses of the antibiotic ceftriaxone show no clear benefit over the standard 1-gram daily dose for curing infections in adults, based …
Meta-analysis finds 30.7% molecular prevalence of yellow fever virus in non-human primates
Infectious Disease Meta-analysis
Meta-analysis finds 30.7% molecular prevalence of yellow fever virus in non-human primates Yellow fever virus found in many monkeys in the Americas, study shows
A meta-analysis of 39 studies involving 7,183 non-human primates found pooled molecular prevalence of yellow fever virus infection was 30.7%…
Yellow fever virus was found in 31% of monkey samples and 43% of tissue tests, with infected animals in detailed cases all dying from severe…
Short-course antibiotic therapy shows comparable outcomes to extended courses in ICU patients with MDR Gram-negative infections
Infectious Disease Meta-analysis
Short-course antibiotic therapy shows comparable outcomes to extended courses in ICU patients with MDR Gram-negative infections Can critically ill patients safely take shorter courses of powerful antibiotics?
A meta-analysis of 602 critically ill ICU patients found no significant difference in mortality or clinical failure between short-course (6-…
Critically ill patients with tough infections may safely take shorter antibiotic courses, though relapse risk warrants further study.