Clinical prediction model for 1-year ischemic stroke recurrence developed from Chinese cohort data
New Tool Predicts Second Stroke Risk Within One Year
This observational cohort study developed a clinical prediction model for 1-year recurrence after first-ever ischemic stroke in 738 patients…
This research gives doctors a simple way to spot stroke survivors who are most likely to have another stroke, so they can intervene sooner.
Elevated Plasma P-tau217 Associated with Cognitive Impairment Onset Up to Four Years Before in Preclinical Alzheimer's
Alzheimer’s May Be Predicted Years in Advance
This observational cohort study evaluated individuals with preclinical cognitive decline in Alzheimer's Disease. Elevated plasma P-tau217 le…
Maria started forgetting names. Not just once or twice—her daughter noticed a pattern.
Real-World Evidence on Herbal Medicine Prescriptions for Stroke Sequelae in Korean Cohort
Herbal medicine linked to symptom stability in stroke patients
This retrospective cohort study analyzed 942 patients with cerebrovascular disease sequelae using Korean claims data. Reimbursed herbal medi…
Many stroke survivors taking herbal medicine remained stable or improved slightly during a large Korean health insurance review.
Individualized probabilistic migraine forecasts delivered via electronic diaries in adults with recurrent headaches
Migraine Forecasting Just Got Smarter
This prospective cohort study of 230 adults with recurrent migraine or tension-type headache evaluated individualized probabilistic forecast…
This tool could help you prepare for migraines before they strike.
SONNET 2 and RONDO 3 processors improve sentence recognition in noise for Mandarin-speaking cochlear implant users.
New Cochlear Implants Boost Speech Clarity for Mandarin Speakers
This prospective single-subject repeated-measures cohort study in 51 native Mandarin-speaking cochlear implant users found that upgraded aud…
Mandarin speakers can hear speech more clearly with newer cochlear implant processors.
Machine learning model for mortality prediction in ICU traumatic brain injury patients
New AI Model Predicts Brain Injury Death Risk Better
This observational cohort study from the MIMIC-IV database developed an interpretable machine learning model to predict in-hospital mortalit…
A new computer tool helps doctors understand survival chances for brain injury patients more clearly.
Retrospective study of endovascular treatment for sICAS shows no significant difference in 30-day stroke or death between early and delayed groups.
Timing of treatment did not change stroke risk for patients with brain vessel blockages.
This retrospective single-center study analyzed 174 consecutive patients with symptomatic intracranial atherosclerotic stenosis undergoing i…
For people with blocked brain vessels, getting endovascular treatment early versus later did not significantly lower the risk of stroke or d…
Longitudinal multimodal MRI identifies Friedreich ataxia progression subtypes in 111 patients and controls.
Three distinct brain patterns linked to Friedreich ataxia progression.
This observational cohort study analyzed 111 participants, including 54 Friedreich ataxia patients and 57 controls, using longitudinal multi…
Three distinct brain patterns linked to Friedreich ataxia progression were identified using MRI scans and genetic data in patients.
CSF SAA status associates with levodopa responsiveness and motor progression in Parkinson's disease patients.
Parkinson’s test predicts levodopa response and motor decline speed
This observational cohort study analyzed 223 sporadic Parkinson's disease participants from the PPMI cohort initiating levodopa. SAA+ patien…
Test reveals Parkinson’s patients with alpha-synuclein seeds respond better to levodopa and decline slower than those without the seeds.
Scoping Review Summarizes COP Biofeedback Interventions for Chronic Stroke Fall Prevention
Biofeedback Linked to Lower Fall Risk in Stroke Survivors
This scoping review synthesizes evidence from nine studies involving 306 participants regarding center of pressure interventions for adult s…
Stroke survivors face high fall rates. Biofeedback helps reduce sway and may significantly lower injury risk after discharge.
Prospective observational study of VNS in drug-resistant epilepsy patients with or without prior intracranial surgery
Failed Brain Surgery? This Device Might Still Stop Seizures
This prospective, multicenter, international observational study abstract evaluates vagus nerve stimulation (VNS) in 531 patients with drug-…
Patients who had brain surgery but still have seizures can still benefit from nerve stimulation therapy.
Secondary analysis of pooled ALS trial data reveals entropy-based functional domain trajectories
New Method Reveals Hidden Treatment Signals in ALS Trials
This secondary analysis of pooled clinical trial data from the PRO-ACT database examined Shannon entropy trajectories of ALSFRS functional d…
This study suggests that the way we measure success in ALS clinical trials might be hiding real treatment benefits, and a new mathematical a…