Capivasertib-paclitaxel fails to improve overall survival in metastatic TNBC
New drug combo did not extend life for metastatic triple-negative breast cancer patients in this trial
This phase III RCT in 812 patients with previously untreated metastatic triple-negative breast cancer found that adding capivasertib to pacl…
A large global trial found that adding capivasertib to paclitaxel did not improve overall survival for patients with metastatic triple-negat…
Systematic review of post-traumatic growth in 6382 breast cancer patients
Post-traumatic growth is common among breast cancer survivors and linked to better coping
This systematic review and meta-analysis examines post-traumatic growth (PTG) among 6382 breast cancer patients. The authors synthesize evid…
A large review finds post-traumatic growth is nearly universal in breast cancer survivors and connects to lower distress and stronger resili…
Systematic review and meta-analysis of axillary staging in node-positive breast cancer patients
Sentinel Node Biopsy Shows Similar Survival to Axillary Dissection in Breast Cancer
This systematic review and meta-analysis evaluated sentinel lymph node biopsy versus targeted axillary dissection in node-positive breast ca…
A meta-analysis of 2,849 patients found that sentinel lymph node biopsy offered similar overall survival to targeted axillary dissection for…
Network meta-analysis shows exercise interventions improve cognitive function in breast cancer patients
Mind-body exercise beats aerobic work for brain fog in breast cancer
This network meta-analysis evaluated exercise interventions for patients with breast cancer. The authors synthesized data from 1440 particip…
New research shows mind-body exercise clears brain fog better than running or walking for breast cancer patients.
Meta-analysis finds acupuncture improves pain and function in cervical cancer patients
Acupuncture helps cervical cancer patients feel less pain and move better
This systematic review and meta-analysis of 627 cervical cancer patients found that acupuncture combined with conventional treatment signifi…
New research shows adding acupuncture to standard care significantly reduces pain and improves daily function for women with cervical cancer…
In-person group sessions boost fruit/vegetable intake in Latina breast cancer survivors
In-Person Sessions Boost Fruit and Vegetable Intake in Latina Breast Cancer Survivors
This randomized factorial trial in 167 Latina breast cancer survivors found that in-person group sessions increased daily fruit/vegetable in…
In-person group sessions helped Latina breast cancer survivors eat more fruits and vegetables, while the control group's intake dropped shar…
Higher shoulder joint radiation dose linked to worse arm morbidity in breast cancer patients with SLN macrometastases
High radiation doses to the shoulder may cause long-term arm pain in breast cancer patients
This randomized trial evaluated 868 patients with breast cancer and 1-2 sentinel lymph node macrometastases in a Swedish setting. Higher nea…
New data shows that higher radiation doses near the shoulder joint can lead to lasting arm pain and stiffness in breast cancer survivors
Tandem-ring applicator lowers rectal and sigmoid doses compared to tandem-ovoid in cervical cancer patients
New applicator lowers radiation to rectum in cervical cancer treatment
This randomized controlled trial enrolled 36 eligible patients who completed pelvic external beam radiotherapy. The study compared tandem-ri…
A small trial found a tandem-ring applicator reduced radiation dose to the rectum and sigmoid colon compared to a tandem-ovoid device during…
Contrast-enhanced mammography reduces costs per QALY in breast cancer screening recalls compared to conventional imaging
Contrast-enhanced mammography may cut costs for breast cancer screening
This RCT evaluated women recalled from breast cancer screening in a hospital setting. Contrast-enhanced mammography (CEM) as the primary too…
Using contrast-enhanced mammography as the first test for women recalled from screening could lower imaging costs without harming quality of…
Meta-regression of cervical cancer brachytherapy applicators shows interstitial needles improve target dose objectives
Adding needles to cervical cancer treatment boosts target dose for most patients
This systematic review and meta-regression analyzed 34 studies from clinical practices regarding cervical cancer brachytherapy. The authors …
Adding needles to standard cervical cancer radiation tools improved target dose for most patients without hurting nearby organs, based on da…
Systematic review finds inconclusive links between pregnancy factors and breast cancer risk in daughters
Pregnancy factors linked to breast cancer risk in daughters remain uncertain
This meta-analysis evaluated associations between maternal and paternal age, gestational age, twin status, and maternal preeclampsia with br…
A large review of fifty-two studies found inconclusive links between pregnancy factors and breast cancer risk in daughters.
Nalbuphine and midazolam show non-inferiority to pethidine and midazolam for oocyte retrieval pain
Nalbuphine Matches Old Painkiller For Egg Retrieval
In this double-blinded, non-inferiority randomized controlled trial of 94 participants, 10 mg intravenous nalbuphine with 5 mg midazolam was…
A new painkiller matches the old standard for egg retrieval without causing more side effects.