Low baseline TKa associated with longer OS of 38.5 months in endocrine-resistant MBC
Low thymidine kinase levels linked to longer survival in breast cancer
This translational analysis of a Phase III trial involving 555 patients with endocrine-resistant HR+ / HER2- metastatic breast cancer found …
A specific enzyme level called thymidine kinase may help doctors predict how well patients with certain types of breast cancer will respond …
Zinc supplementation shows potential in reducing severe radiation-induced oral mucositis in head and neck cancer patients
Zinc Mouthwash May Reduce Severe Mouth Sores From Radiation
Researchers evaluated the impact of topical and systemic zinc on the incidence of severe radiation-induced oral mucositis in head and neck c…
A new analysis suggests zinc mouthwash may cut the risk of severe mouth sores from radiation by 84%.
HPV prevalence in breast cancer tissue is 23% with higher risk in specific subtypes
Analysis shows link between HPV and breast cancer tissue
This meta-analysis of 82 studies involving 7,683 samples found a 23% prevalence of HPV in breast cancer tissues. The analysis identified sig…
A large analysis of over 7,000 samples reveals a significant link between the human papillomavirus and certain types of breast cancer.
Asparaginase therapy in acute lymphoblastic leukemia patients correlates with increased thromboembolism risk in specific subgroups
Adults with Leukemia Show Higher Risk of Blood Clots
This meta-analysis examined the incidence of thromboembolism among patients with acute lymphoblastic leukemia receiving asparaginase based c…
Patients with acute lymphoblastic leukemia treated with asparaginase face higher risks of blood clots, especially adults and those with spec…
Hybrid multi-component frameworks and qualitative integration characterize best practices in medical device risk management
Review Identifies Best Practices for Medical Device Risk Management
This scoping review analyzed 12 documents to identify best practices in medical device risk management. The authors found that while ISO 149…
New research highlights the need for more patient input and stakeholder engagement to improve safety in medical device manufacturing.
Robotic nipple-sparing mastectomy increases total operative time by 64.01 minutes compared to conventional techniques
Robotic surgery takes longer for breast reconstruction but keeps safety
This meta-analysis of prospective studies compares robotic versus conventional nipple-sparing mastectomy for patients undergoing immediate i…
Robotic-assisted breast reconstruction may take significantly longer than traditional methods, though it shows similar safety results for pa…
Cadmium exposure increases pancreatic cancer risk with an RR of 1.69 across meta-analyzed data
Cadmium exposure linked to 69% higher pancreatic cancer risk
This meta-analysis evaluates the link between cadmium exposure from various sources and pancreatic cancer incidence. The analysis found that…
People exposed to cadmium may face a 69% higher risk of pancreatic cancer, a new analysis finds.
Mendelian Randomization Evaluates IL-6 Inhibition Effects on Hepatocellular and Colorectal Cancer Risk
Genetic data shows tocilizumab does not cause specific cancers
Genetic modeling suggests that IL-6 inhibition does not causally increase the risk of hepatocellular or colorectal cancers in diverse popula…
New genetic modeling suggests the drug tocilizumab does not increase the risk of liver or colorectal cancers for patients.
Machine learning models provide statistically significant improvements in 5-year survival prediction for gastric cancer patients
AI Models Slightly Improve Gastric Cancer Survival Prediction
This systematic review and meta-analysis of 10 retrospective studies evaluated AI models using electronic health record data to predict 5-ye…
AI models modestly beat standard tools at predicting 5-year survival after gastric cancer surgery, a new meta-analysis finds.
FH-deficient uterine leiomyoma in young women requires IHC screening and lifelong renal surveillance
Rare Genetic Marker Linked to Multiple Uterine Fibroids
This case report and literature review describes a 35-year-old woman with multiple uterine leiomyomas confirmed as FH-deficient via immunohi…
A rare genetic condition can cause multiple uterine fibroids in young women and may require lifelong monitoring for other health issues.
Prostatic incidental uptake on FDG PET/CT has a 1.7% prevalence with 21.3% malignancy risk
New data helps doctors identify prostate cancer risks on scans
This meta-analysis of 24 studies evaluates the prevalence and malignancy risk of prostatic incidental uptake (PIU) on various radiotracers. …
Doctors are finding ways to better distinguish between harmless activity and actual cancer during routine prostate scans.
Hypopharyngeal well-differentiated liposarcoma can occur in young adults and may recur early after transoral excision
Rare Liposarcoma Can Recur Quickly After Surgery in Young Adults
This case report and literature review describes a 24-year-old man with a hypopharyngeal mass that was histopathologically confirmed as well…
A rare type of liposarcoma can appear in young adults and may return quickly after surgery, highlighting the need for careful monitoring.