Case report details KFD patient developing SLE treated with immunosuppression
Your stomach hurts. You throw up. You think it is just food poisoning. But what if your immune system is fighting a hidden battle inside your lymph nodes? This story is about a rare condition that tricks doctors and changes a patient's life forever.
This case report describes a single patient with Kikuchi-Fujimoto disease who subsequently developed systemic lupus erythematosus. The autho…
Severe stomach pain and vomiting from a rare immune disorder can hide a hidden battle in your lymph nodes that tricks doctors into missing t…
Surgery improves tracheal morphology in pediatric pulmonary artery sling cases
CT Scans Show Real Tracheal Healing After Sling Surgery
A retrospective cohort study of 17 pediatric patients with pulmonary artery sling at Fujian Children's Hospital found that surgery significa…
New scans show surgery successfully widens the airways in children with a rare heart condition, giving doctors a clear map of healing.
Standardized formal resuscitation training likely reduces neonatal mortality in low- and middle-income countries compared to no training or basic training.
A Simple Training Program Is Saving Newborn Lives in Poor Countries
This meta-analysis of randomized controlled trials and quasi-randomized trials involving over 528,000 newborns in low- and middle-income cou…
A simple training program for newborn resuscitation cuts 24-hour infant death rates by 27% in low- and middle-income countries, according to…
Melatonin treatment in term or late preterm newborns with neonatal encephalopathy shows very uncertain effects on mortality or disability.
Could Melatonin Protect Newborn Brains? We Still Don't Know
This systematic review and meta-analysis evaluated melatonin in newborns with neonatal encephalopathy. Based on one pilot study, evidence re…
Melatonin shows promise in animal studies for protecting newborn brains from oxygen injury, but human trials are too few to guide treatment …
Physical activity improves motor skills and body composition in children with intellectual disabilities
Movement Is Medicine for Kids With Developmental Disabilities — Here's the Proof
A meta-analysis of 5,245 children and adolescents with intellectual and developmental disabilities found that physical activity significantl…
Structured exercise significantly improves movement skills and body composition in children with intellectual and developmental disabilities…
Exercise improves motor function in children with cerebral palsy, with optimal dose range identified
The Right Exercise Dose for Kids With Cerebral Palsy Finally Has a Number
A Bayesian network dose-response meta-analysis of 20 RCTs in children and adolescents with cerebral palsy found that exercise interventions …
A rigorous analysis of 20 clinical trials reveals the optimal exercise dose range that improves movement in children with cerebral palsy — a…
AMR strategies in LMIC newborns reduce antibiotic use and mortality in meta-analysis
Strategies to reduce antibiotic resistance may lower infection risks in newborns in low-income countries
A systematic review and meta-analysis of 31 facility-based studies in LMICs found that strategies to reduce antimicrobial resistance, includ…
Strategies to curb antibiotic resistance in newborns in low-income countries lower infection risks and reduce overall mortality.
Protocol for trial of structured motor PE versus ordinary PE in preschool children
What Happens to a Toddler's Brain During Gym Class
This protocol describes a planned cluster-randomized controlled trial in approximately 110 preschool children in China. It will compare stru…
A new trial tests if game-based gym class for 4-to-6-year-olds improves brain function using wearable sensors to measure attention and self-…
Short-term psycho-behavioral training shows improvements in autistic children across multiple domains
A Four-Week Program That Helped Autistic Kids Speak Up
A randomized controlled trial of 101 autistic children aged 1-7 years found that a 4-week, 20-session core feature target intervention (CFTI…
A four-week family therapy program helped young autistic children improve speech, social skills, and behavior after just 20 sessions.
Meta-analysis finds increased VTE risk in pediatric IBD, especially ulcerative colitis
Kids with Bowel Disease Face a Hidden Blood Clot Risk Adults Miss
A systematic review and meta-analysis of over 100,000 children and teenagers with IBD found a significantly increased risk of venous thrombo…
Children with Crohn's or ulcerative colitis face nearly seven times the blood clot risk of healthy kids, yet prevention guidelines for teens…
Behavioral oral health interventions improve knowledge and hygiene but not calculus in children
Do Oral Health Lessons Actually Help Kids' Teeth?
A meta-analysis of 44 quasi-experimental studies in children found behavior-based oral health interventions significantly improved knowledge…
A review of 44 studies shows that teaching kids about oral health really does improve their brushing habits and gum health, but hardened bui…
SELFIE intervention shows variable cost-effectiveness for youth self-esteem after childhood adversity
Study examines cost-effectiveness of a self-esteem app for youth with low self-esteem and childhood adversity.
An RCT in youth aged 12-26 years with low self-esteem and childhood adversity found SELFIE had a societal ICUR of €53,986 per QALY gained, w…
A self-esteem app for youth with childhood adversity saved money only for those already in specialized mental health care, while costing tho…