HFNC reduces oxygen desaturation and procedure interruptions during bronchoscopy in high-risk patients
High-flow oxygen during bronchoscopy reduces breathing problems in high-risk patients
A meta-analysis of RCTs involving 1,054 high-risk patients undergoing bronchoscopy found high-flow nasal cannula (HFNC) significantly reduce…
High-flow oxygen during bronchoscopy cuts dangerous breathing drops and interruptions for high-risk patients with lung disease or obesity.
Antenatal dexamethasone reduces respiratory support need in late preterm infants in Vietnamese RCT
Can a steroid shot before late preterm birth help babies breathe easier?
A randomized controlled trial of 294 pregnant women at risk of late preterm delivery in Vietnam found antenatal dexamethasone reduced infant…
Giving mothers a steroid shot before late preterm birth cut the need for breathing support in babies by nearly 10%, reducing hospital stays …
Lung cancer trial patients show disparities in optional biospecimen study participation
Who gets left out when cancer patients are asked to donate tissue for research?
An observational analysis of 3017 patients in two phase 3 lung cancer trials found 89% agreed to participate in optional biospecimen studies…
Women and racial minorities in lung cancer trials are less likely to donate tissue samples, risking that future research misses the very peo…
ERAS-guided refined nursing associated with earlier mobilization after lung cancer surgery in retrospective cohort
Could a new nursing approach help lung cancer surgery patients get moving faster?
A retrospective cohort study of 136 patients undergoing radical lung cancer surgery found ERAS-guided refined nursing was associated with si…
A new nursing approach helps lung cancer surgery patients get out of bed and walk sooner, perform better on mobility tests, and recover fast…
Phase 2 trial of high-dose thoracic reirradiation shows 30-month median OS for recurrent lung cancer
Can high-dose radiation help when lung cancer returns near where it was treated before?
A phase 2 single-arm trial of 60 patients with recurrent lung cancer in the thorax found that high-dose reirradiation (≥45 Gy EQD) achieved …
When lung cancer returns near a previous radiation site, a precise high-dose treatment helped patients survive a median of 30 months with no…
Phase 2 trial finds no significant PFS benefit adding SABR to nivolumab in advanced NSCLC
Does adding targeted radiation to immunotherapy help advanced lung cancer?
A phase 2 randomized trial in 50 adults with metastatic NSCLC found no significant difference in 6-month progression-free survival (49% vs 4…
Adding high-dose radiation to immunotherapy did not improve outcomes or reduce side effects for advanced lung cancer patients who had alread…
Vitamin D3 supplementation improved exercise tolerance in deficient male COPD patients in small RCT
Vitamin D supplements linked to better walking ability in men with COPD and low vitamin D
A 26-week double-blind RCT in 40 vitamin D3-deficient male COPD patients found that oral vitamin D3 supplementation (80,000 IU/week then adj…
Men with COPD and low vitamin D levels walked farther and felt less breathless after taking supplements for six months.
Amivantamab-lazertinib shows OS benefit over osimertinib in Asian EGFR-mutant NSCLC subset
Combination therapy shows longer survival than standard drug in Asian lung cancer patients
In a subset analysis of an RCT of 629 Asian patients with untreated EGFR-mutant advanced NSCLC, amivantamab-lazertinib prolonged overall sur…
Asian lung cancer patients on a new two-drug combination therapy lived longer than those taking the standard single drug, with a 26% lower r…
Acute high-intensity inspiratory muscle training linked to shorter oxygen desaturation time in COPD
Small COPD study finds different breathing exercises affect muscle oxygen differently
A randomized crossover study in 29 individuals with COPD found acute high-load IMT was associated with shorter oxygen desaturation time comp…
High-intensity breathing exercises may drop arm muscle oxygen faster than lower-intensity training in people with COPD, while endurance trai…
FDA Approves Winrevair for Pulmonary Arterial Hypertension (PAH) in Adults
FDA approves a new treatment for a serious lung condition called pulmonary arterial hypertension
The FDA has approved Winrevair for the treatment of adults with pulmonary arterial hypertension (PAH, WHO Group 1) to improve exercise capac…
A new FDA-approved injection helps adults with pulmonary arterial hypertension exercise longer, improve daily life, and lower the risk of ho…
Capmatinib shows efficacy in Chinese NSCLC patients with MET exon 14 skipping mutations
Could a targeted pill help Chinese patients with a specific lung cancer mutation?
An open-label, multicenter phase II study evaluated capmatinib in 36 Chinese adult patients with advanced NSCLC harboring MET exon 14 skippi…
A targeted pill shrank tumors in Chinese lung cancer patients with a specific MET gene mutation, offering a new treatment option for this ge…
Phase 2 trial of neoadjuvant/adjuvant pembrolizumab in stage IB-IIIA NSCLC completes enrollment of 35 patients
Can immunotherapy before lung cancer surgery help the immune system fight the tumor?
A multi-institutional phase 2 trial has completed enrollment of 35 patients to study neoadjuvant and adjuvant pembrolizumab in stage IB, II,…
Doctors tested giving immunotherapy before lung cancer surgery to see if it safely boosts the immune system's ability to fight the tumor.