Untargeted urinary proteomics identifies dysregulated biomarkers in women with endometrial cancer versus controls.
New Urine Test Could Spot Endometrial Cancer Early
This case–control study evaluated untargeted label-free LC-MS/MS mass spectrometric approaches combined with bioinformatics in 40 women (20 …
A new urine test analyzes hundreds of proteins to spot endometrial cancer early without invasive biopsies.
Guideline reviews perioperative immunotherapy for hepatocellular carcinoma after resection or ablation
A New Strategy Emerges to Stop Liver Cancer From Coming Back
A guideline reviews perioperative immunotherapy for hepatocellular carcinoma after resection or ablation. Adjuvant atezolizumab plus bevaciz…
Doctors are finding smarter ways to use the body’s own immune system around the time of surgery to give patients with liver cancer a better …
Biological DMARDs show marginal patient-reported outcome benefits over conventional therapy in early rheumatoid arthritis
Early rheumatoid arthritis patients report similar symptom relief with different treatment approaches
This open-label randomized trial in 795 newly diagnosed, DMARD-naïve RA patients compared three biological DMARDs plus methotrexate against …
In early rheumatoid arthritis, patients reported similar pain relief and quality-of-life improvements whether they started with conventional…
Anifrolumab shows higher remission rates versus placebo in SLE patients regardless of immunosuppressant history
A New Lupus Drug May Work Better If You Start It Sooner
A post hoc analysis of pooled Phase 3 RCT data in 726 patients with moderate-to-severe SLE found higher DORIS remission rates with anifrolum…
Starting a new lupus drug before trying older medications may help patients reach remission faster and with fewer side effects.
VATS and hormonal therapy for diaphragmatic endometriosis in a 42-year-old woman with hepatic herniation
Can surgery alone fix rare chest pain caused by endometriosis, or is a team approach needed?
This case report and literature review describes a 42-year-old woman with diaphragmatic endometriosis, hepatic herniation, and catamenial pn…
A 42-year-old woman's rare chest pain from endometriosis required both surgery and hormones, proving that surgical repair alone may not be e…
Antimicrobial peptides show anticancer activity via membrane disruption and immune priming in preclinical models
Review finds antimicrobial peptides show promise against cancer cells but clinical evidence remains limited
A systematic review of preclinical evidence finds antimicrobial peptides (AMPs) exhibit selective electrostatic interactions with malignant …
Antimicrobial peptides can selectively target and kill cancer cells by disrupting their membranes while also acting as vaccines to boost the…
Functional precision medicine approaches may complement current paradigms for non-metastatic colorectal cancer management.
Your Colon Cancer Treatment Plan May Be Missing This One Crucial Piece
This commentary discusses functional precision medicine approaches, genomic profiling, and ex vivo drug responses in patients with non-metas…
Standard colon cancer plans often miss unique biology that drives recurrence, prompting calls for new approaches beyond current guidelines.
Proceeding with TKA without preoperative anticoagulation for asymptomatic calf vein thrombosis shows no 90-day VTE events
Skip the delay for a minor clot before knee surgery
A retrospective cohort study of 454 adults undergoing primary unilateral TKA found that 44 patients with preoperative asymptomatic isolated …
A small, silent clot found before knee replacement does not require stopping surgery or adding extra blood thinners.
Retrospective study identifies predictors of prolonged ventilation after basal ganglia hemorrhage surgery
One in Three Brain Bleed Patients Face Weeks on a Ventilator — Who's Most at Risk?
A retrospective cohort study of 173 adult ICU patients who underwent surgery for hypertensive basal ganglia intracerebral hemorrhage found t…
About one in three patients recovering from brain bleed surgery need a breathing machine for two weeks or longer, with older age and kidney …
Modified anal fistula plug with drainage seton shows early recovery benefits and comparable 12-month outcomes to conventional treatment in cryptoglandular anal fistula.
A New Plug for Anal Fistulas Cuts Pain and Speeds Healing
This prospective cohort study evaluated 140 patients with cryptoglandular anal fistula treated with a modified anal fistula plug combined wi…
A modified anal fistula plug helps patients heal faster with less pain after surgery, offering a smoother recovery for those dealing with th…
PRO and Serum Biomarker Models Predict Endoscopic Activity in Ulcerative Colitis
Count Your Stools to Spot Flare-Ups Early
A retrospective multicenter cohort study of 297 UC patients developed models using patient-reported outcomes (stool frequency, rectal bleedi…
Counting your daily stools and bleeding can accurately spot ulcerative colitis flare-ups without needing an invasive colonoscopy.
Retrospective cohort finds 25-gauge vitrectomy achieves complete foreign body removal in all 198 eyes
What happens when metal enters the eye? A surgery study shows who gets hurt.
A retrospective cohort of 198 patients undergoing 25-gauge pars plana vitrectomy for intraocular foreign body (IOFB) extraction achieved 100…
A study of nearly 200 eye injuries found metal objects were removed in every surgery, with most patients being young or middle-aged men in r…