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Phase 3 N=62 Randomized Double-blind Prevention

Montelukast for Early Life Wheezing

Lung Diseases · Asthma

Enrolled (actual)
62
Serious AEs
0.0%
Results posted
Feb 2017
Primary outcome: Primary: Number of Wheezing-free Days of Infant (Observed by Primary Caregiver) — 25.5; 30.5 Days

Study Design & Population

Study type
Interventional
Phase
Phase 3
Interventions
Montelukast (Drug); Placebo (Drug)
Age
Pediatric · 0+ yrs
Sex
All
Sponsor
University of Massachusetts, Worcester
Primary completion
Oct 2016

Outcome Measures

OutcomeResultp-value
PRIMARY
Number of Wheezing-free Days of Infant (Observed by Primary Caregiver)
25.5; 30.5
SECONDARY
Wheezing at Day 7
10; 22
SECONDARY
The Number of Participants Requiring Rescue Beta Agonist Use
15; 26

Summary

This study will determine the effects of montelukast on the duration of wheezing in children 12 months to 3 years of age who visit a physician for care of a wheezing illness. Only patients from the Ankara area of Hacettepe University Medical Center in Turkey will be included in this study.

Eligibility Criteria

Inclusion Criteria

  • Physician-diagnosed wheezing illness

Exclusion Criteria

  • Asthma
  • Prematurity
  • Known intolerance to montelukast
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00115297). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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