N/A
Completed N=103
Innovation in Pulmonary Rehabilitation
Chronic Obstructive Pulmonary Disease · Pulmonary Emphysema
Source: ClinicalTrials.gov NCT00123422 ↗
Enrolled (actual)
103
Serious AEs
5.8%
Results posted
Oct 2014
Primary outcomePrimary: Exercise Endurance — 18.1; 14.5; 11.5 minutes — p=0.015
Summary
The purpose of this study was to compare the effect of exercise treatment combined with breathing retraining (a computerized feedback program), with exercise treatment combined with heliox (a helium and oxygen combination), with exercise only in patients with moderate to severe chronic obstructive pulmonary disease. This was an 8-week intervention study.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Exercise Endurance |
18.1; 14.5; 11.5 | 0.015 sig |
| SECONDARY Inspiratory Capacity |
2.4; 2.0; 2.1 | <0.05 sig |
Eligibility Criteria
Inclusion Criteria
- 40 years of age
- FEV1 70%
- FEV1/FVC 120%
Exclusion Criteria
- Respiratory infection/exacerbation within last 4 weeks
- Exercise limiting heart disease
- Primary asthma
- Congestive heart failure New York Heart Association (NYHA) Class III-IV
- Exercise limiting peripheral arterial disease or arthritis
- Inability to walk on a treadmill
Data sourced from ClinicalTrials.gov (NCT00123422). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.