Phase 3
N=142
Radial Artery Versus Saphenous Vein Patency (RSVP) Study
Coronary Arteriosclerosis
Bottom Line
View on ClinicalTrials.gov: NCT00139399 ↗Enrolled (actual)
142
Serious AEs
16.9%
Results posted
Jun 2019
Primary outcome: Primary: Patency Rates — 38; 58; 6; 1 Participants
Study Design & Population
- Study type
- Interventional
- Phase
- Phase 3
- Interventions
- Coronary artery bypass graft (CABG) surgery (Procedure)
- Age
- Adult, Older Adult · 40+ yrs
- Sex
- All
- Sponsor
- Imperial College London
- Primary completion
- Jul 2006
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Patency Rates |
38; 58; 6; 1 | — |
| PRIMARY Mean Diameter of the Study Graft (Saphenous Vein or Radial Artery) |
3.18; 2.7 | — |
| SECONDARY Blood Flow Volume |
39; 44 | — |
Summary
The purpose of this study is to determine whether the radial artery (artery in the arm) or saphenous vein (vein in the leg), when used as bypass grafts for coronary artery bypass surgery, have a greater patency rate (degree of opening)at 5 years after surgery.
Eligibility Criteria
Inclusion Criteria
- on waiting list for clinically-indicated myocardial revascularization surgery
- aged 40-70 years
- significant stenosis (≥70%) in the circumflex territory as identified on preoperative angiograms
- negative Allen's test (defined as the return of palmar circulation within 5 seconds of releasing ulnar artery compression)
- willing to give written informed consent
Exclusion Criteria
- poor left ventricular (LV) function (LV ejection fraction <25%)
- severe diffuse peripheral vascular disease or bilateral varicose venous disease
- inability to comply with the angiographic follow-up at 3 months or/and 5 years
Data sourced from ClinicalTrials.gov (NCT00139399). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.