N/A
N=119
Long-term Behavior Change - 1
Amphetamine-related Disorders
Bottom Line
View on ClinicalTrials.gov: NCT00158197 ↗Enrolled (actual)
119
Serious AEs
2.1%
Results posted
Jul 2014
Primary outcome: Primary: Methamphetamine Use During Intervention — 65.17; 60.35; 57.74; 42.81 percentage of negative urine samples — p=<0.01
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- contingency management voucher (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Friends Research Institute, Inc.
- Primary completion
- Jun 2008
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Methamphetamine Use During Intervention |
65.17; 60.35; 57.74; 42.81 | <0.01 sig |
| PRIMARY Methamphetamine Use, Measured by Number of Consecutive Days of Abstinence |
22.42; 22.7; 20.32; 11.10 | 0.02 sig |
| PRIMARY Methamphetamine Use, Follow-Up |
90.79; 88.89; 88.62; 87.30 | 0.78 |
Summary
The purpose of this study is to determine if different reinforcement procedures (i.e., schedules) produce different patterns of long-term abstinence from methamphetamine. We anticipate that the three contingency management conditions will promote longer periods of abstinence in the year following treatment relative to the standard control group. Furthermore, we predict that the intermittent reinforcement procedures will produce longer periods of continued abstinence (i.e., long-term behavior change) in the year following treatment than the continuous reinforcement procedure. Finally, we predict that the intermittent unpredictable schedule will produce longer lasting behavior change than the intermittent predictable schedule. Methamphetamine use will be measured using urine toxicology and self-report of methamphetamine use.
Eligibility Criteria
Inclusion Criteria
- Meet Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) criteria for methamphetamine dependence
- Willing and able to comply with study procedures
- Willing and able to provide written informed consent
Exclusion Criteria
- Have a medical condition that, in the study Principal Investigator (PI's) judgment, might interfere with safe study participation
- Have a recent (past 30 days) history of suicide attempts and/or current serious suicidal intention or plan as assessed by the Beck Depression Inventory (BDI)
- Have a history of violent criminal behavior or be on parole
- Any other circumstances that, in the opinion of the PI, would interfere with safe study participation
Data sourced from ClinicalTrials.gov (NCT00158197). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.