Phase 4
Completed N=50
Airway Clearance for Prevention of Chronic Obstructive Pulmonary Disease (COPD) Exacerbation
Source: ClinicalTrials.gov NCT00181207 ↗Enrolled (actual)
50
Serious AEs
0.0%
Results posted
Oct 2018
Primary outcomePrimary: The Primary Outcome Measure is the Rate of Exacerbations as Defined Using the Winnipeg Criteria. — 5.5; 4 exacerbations per 12 weeks
◆ Published Evidence
No publication linked
No peer-reviewed publication reporting this trial's results has been linked yet. This can indicate results are unpublished — a known publication-bias signal. We re-check periodically.
Summary
The purpose of this study is to show that one form of mechanical airway clearance techniques, High Frequency Chest Wall Oscillation (HFCWO)using a pneumatic vest, will diminish exacerbations of COPD which will improve respiratory health status.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY The Primary Outcome Measure is the Rate of Exacerbations as Defined Using the Winnipeg Criteria. |
5.5; 4 | — |
| SECONDARY Quality of Life |
5; 0 | — |
Eligibility Criteria
Inclusion Criteria
- Physician Diagnosis of COPD, chronic bronchitis and/or emphysema
- Forced Expiratory Volume in 1 second (FEV1)/ Forced Vital Capacity (FVC) or = 20 pack years
- History of 1 or more COPD exacerbations in past 6 months necessitation hospitalization, Emergency Department (ED) visit, antibiotic or steroid prescription
Exclusion Criteria
- Other lung diseases
- Co-morbid illnesses such as cancer, liver disease, cardiomyopathy
- Recent chest wall or abdominal trauma or surgery that would preclude using the vest
Data sourced from ClinicalTrials.gov (NCT00181207). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.