N/A
N=52
Chest Wall Oscillation for Asthma and COPD Exacerbations Trial (COAT)
Asthma · Chronic Obstructive Pulmonary Disease (COPD) · Undifferentiated Asthma/COPD
Bottom Line
View on ClinicalTrials.gov: NCT00181285 ↗Enrolled (actual)
52
Serious AEs
0.0%
Results posted
Aug 2018
Primary outcome: Primary: Patient Adherence to High Frequency Chest Wall Oscillation — 93; 91 Percent of 60 minutes prescribed
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- High Frequency Chest Wall Oscillator (Device)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- University of Chicago
- Primary completion
- May 2008
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Patient Adherence to High Frequency Chest Wall Oscillation |
93; 91 | — |
| PRIMARY Number of Participants Who Considered the Pneumatic Vest Convenient to Use |
24; 19 | — |
Summary
The objective of this study was to evaluate the use of high frequency chest wall oscillation (HFCWO) early in the treatment of adults hospitalized for acute asthma or chronic obstructive pulmonary disease (COPD).
Eligibility Criteria
Inclusion Criteria
- Age 18 years and older
- Admission to the inpatient medical service
- Physician-diagnosed asthma or asthma/COPD or COPD exacerbation.
- Evidence of airflow obstruction on spirometry
Exclusion Criteria
- More than 24 hours since admission to the inpatient medical service
- Admission to an intensive care unit
- Hospital discharge planned within the next 24 hours
- Other chronic respiratory disease (e.g., sarcoidosis, idiopathic pulmonary fibrosis)
- Chest wall abnormalities (e.g., severe kyphoscoliosis) that precludes using the vest
- Chest wall or abdominal trauma/surgery in the past 6 weeks that precludes using the vest
- Physician declines to provide consent
- Patient unable (e.g., history of cognitive impairment, unable to understand English) or declines to provide consent
- Previous participant in this study
- Corticosteroid therapy (prednisone >0 mg/d equivalent) for >1 week prior to admission
Data sourced from ClinicalTrials.gov (NCT00181285). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.