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N/A N=191 Randomized Single-blind Treatment

Managing Temporomandibular Disorder (TMD) Symptoms

Temporomandibular Joint Disorders

Enrolled (actual)
191
Serious AEs
0.0%
Results posted
Jul 2011
Primary outcome: Primary: Characteristic Pain Intensity (Characteristic Intensity of Facial Pain) — 3.1; 2.9; 3.6 units on a scale — p=0.19

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Self Management (Behavioral); Targeted Self Management (Behavioral); 20 mcg ethinyl estradiol and 100 mcg levonorgestrel (Drug)
Age
Adult · 18+ yrs
Sex
Female
Sponsor
University of Washington
Primary completion
Jun 2010

Outcome Measures

OutcomeResultp-value
PRIMARY
Characteristic Pain Intensity (Characteristic Intensity of Facial Pain)
2.8; 2.8; 3.9 0.003 sig
PRIMARY
Characteristic Pain Intensity (Characteristic Intensity of Facial Pain)
2.8; 2.8; 3.9 0.003 sig
SECONDARY
Number of Participants With Pain-Related Activity Interference
19; 17; 30 0.016 sig
SECONDARY
Number of Participants With Pain-Related Activity Interference
19; 17; 30 0.016 sig

Summary

The purpose of this study is to determine whether treatments targeted to the hormonal factors and the cyclicity of TMD symptoms associated with the menstrual cycle are more effective in relieving TMD pain and symptoms than standard self management treatment.

Eligibility Criteria

Inclusion Criteria

  • TMD Pain Diagnosis as determined by enrollment exam at the University of Washington
  • Menstruate on a regular basis
  • Not planning to become pregnant during the next 6 months

Exclusion Criteria

  • Drug or alcohol abuse
  • Current smoker and 35 years of age at any time during the study
  • Live further than 1 hour driving distance from the University of Washington, Seattle campus
  • Psychiatric disability
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00237042). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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