N/A
Completed N=591
Hypertension Intervention Nurse Telemedicine Study (HINTS)
Source: ClinicalTrials.gov NCT00237692 ↗Enrolled (actual)
591
Serious AEs
40.9%
Results posted
Dec 2014
Primary outcomePrimary: Estimated Percentage of Participants in Blood Pressure Control at Baseline — 61; 59; 53; 64 % of particpants w/ controlled BP
Summary
There are 65 million Americans and over 8.5 million veterans who have been diagnosed with hypertension; yet only 31% of all hypertensive patients have their blood pressure (BP) under effective control (less than 140/90 mm/Hg). Uncontrolled hypertension greatly increases the risk of cerebral vascular accidents, coronary artery disease, myocardial infarction, renal failure, congestive heart failure, and mortality. Despite the damaging impact of hypertension and the availability of well-defined therapies and widely accepted target values for BP, interventions to improve BP control have had limited success.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Estimated Percentage of Participants in Blood Pressure Control at Baseline |
61; 59; 53; 64 | — |
| PRIMARY Estimated Percentage of Participants in Blood Pressure Control at 6 Months |
58; 61; 65; 64 | — |
| PRIMARY Estimated Percentage of Participants in Blood Pressure Control at 12 Months |
60; 73; 73; 69 | — |
| PRIMARY Estimated Percentage of Participants in Blood Pressure Control at 18 Months |
62; 59; 64; 72 | — |
| PRIMARY Blood Pressure Averages Systolic & Diastolic |
127.1; 125.0; 124.7; 122.8; 75.6; 74.9 | — |
Eligibility Criteria
Inclusion Criteria
- Diagnosis of uncontrolled hypertension,
- prescribed a medication to lower blood pressure,
- have a regular primary care physician at Durham VA Medical Center, and
- be a veteran. For Sustainability portion the patient must have participated in an intervention arm of primary study.
Exclusion Criteria
- Hospitalized in past 3 months for stroke,
- heart attack,
- surgery for blocked arteries,
- diagnosed with metastatic cancer or treated with dialysis,
- have a diagnosis of dementia or a hearing impairment which prevents them from being able to hear/speak on the telephone, and
- creatinine serum lab which exceed 2.5.
Data sourced from ClinicalTrials.gov (NCT00237692). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.