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Phase 3 N=137 Randomized Quadruple-blind Treatment

Insomnia and Drug Relapse Risk

Poor Quality Sleep · Opiate Addiction

Enrolled (actual)
137
Serious AEs
0.0%
Results posted
Dec 2013
Primary outcome: Primary: Sleep Quality, as Measured by Total Sleep Time — 339; 329 minutes — p=.05

Study Design & Population

Study type
Interventional
Phase
Phase 3
Interventions
Trazodone (Drug); Placebo (Drug)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Butler Hospital
Primary completion
May 2010

Outcome Measures

OutcomeResultp-value
PRIMARY
Sleep Quality, as Measured by Total Sleep Time
339; 329 .05

Summary

The purposes of this study are: 1. to evaluate the relationship between subjective complaints of sleep and objective measures of sleep quality, as measured through polysomnography, and 2. to evaluate the efficacy of trazodone, as compared to placebo, in individuals early in methadone maintenance.

Eligibility Criteria

Inclusion Criteria

  • Recent methadone maintenance enrollment
  • Sleep complaints as measured by the Pittsburgh Sleep Quality Index (PSQI)
  • No medical contraindications to trazodone

Exclusion Criteria

  • Methadone maintenance enrollment not recent
  • No sleep complaints as measured by the PSQI
  • Medical contraindications to trazodone
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00253890). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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