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N/A N=134 Randomized Single-blind Diagnostic

Reduction of Right Ventricular Pacing Using the Feature Ventricular Intrinsic Preference (VIP)

Bradycardia

Enrolled (actual)
134
Serious AEs
0.4%
Results posted
Jul 2021
Primary outcome: Primary: Percentage of Intrinsic Ventricular Events — 82.7; 22.8 % of intrinsic ventricular events — p=<0.0001

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Intervention/treatment (Device)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Abbott Medical Devices
Primary completion
Sep 2008

Outcome Measures

OutcomeResultp-value
PRIMARY
Percentage of Intrinsic Ventricular Events
82.7; 22.8 <0.0001 sig
SECONDARY
Incidence of Arrhythmias
3.6; 2
SECONDARY
Percentage of Atrial Sensing to Ventricular Sensing (%PR)
41.9; 12.3
SECONDARY
Percentage of Atrial Sensing to Ventricular Pacing (%PV)
8.3; 37.4
SECONDARY
Percentage of Atrial Pacing to Ventricular Sensing (%AR)
40.5; 10.4
SECONDARY
Percentage of Atrial Pacing to Ventricular Pacing (%AV)
10.5; 38.1
SECONDARY
Percentage of Patients Experiencing a Study-Related Adverse Event
0; 2
SECONDARY
Number of Auto Mode Switch Events
3.1; 1.9

Summary

The purpose of this study is to evaluate the efficacy of the VIP™ feature (available in dual chamber Victory® devices) to reduce unnecessary RV pacing, and to determine if patients with implanted SJM pacemakers will benefit by using VIP™ rather than only a programmed AV/PV delay.

Eligibility Criteria

Inclusion Criteria

  • Patient has been implanted with dual chamber SJM Victory® device with VIP™ for 1 month (± 2 weeks).
  • At the time of pacemaker implant, VIP™ is programmed "OFF".
  • At the time of enrollment, patient is paced in the RV ≤ 60% of the time.
  • Patient is medically stable.

Exclusion Criteria

  • Patient has evidence of complete AV block, such that ventricular pacing would be required as part of the patient's routine management.
  • Patient is indicated for AF Suppression.
  • Patient has persistent or chronic atrial fibrillation.
  • Patient is unable to comply with the follow-up visits due to geographical, psychological, or any other reasons.
  • Patient is currently participating in another device research study.
  • Patient is younger than 18 years of age.
  • Patient is pregnant.
  • Patients life expectancy is less than 12 months.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00311168). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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