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Phase 4 N=90 Randomized Quadruple-blind Treatment

Preemptive Local Anesthesia in Vaginal Surgery

Pain, Postoperative

Enrolled (actual)
90
Serious AEs
8.9%
Results posted
Mar 2009
Primary outcome: Primary: Visual Analogue Scale (VAS) Pain Score — 2.5; 4.4 points on a scale — p=.003

Study Design & Population

Study type
Interventional
Phase
Phase 4
Interventions
bupivacaine and epinephrine (Drug); Placebo (Drug)
Age
Adult, Older Adult · 18+ yrs
Sex
Female
Sponsor
Mayo Clinic
Primary completion
Mar 2008

Outcome Measures

OutcomeResultp-value
PRIMARY
Visual Analogue Scale (VAS) Pain Score
2.5; 4.4 .003 sig

Summary

Preemptive analgesia is an intervention which provides an anesthetic prior to initiating a painful stimulus. This trial is examining the effects of a local anesthetic given at the point of innervation prior to performing a vaginal hysterectomy with suspension sutures.

Eligibility Criteria

Inclusion Criteria

  • Women undergoing vaginal hysterectomy with McCall's culdoplasty
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00318292). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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