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N/A N=47 Randomized Treatment

Stage I Randomized Trial of Mentalization-Based Therapy for Substance Using Mothers of Infants and Toddlers

Maternal Substance Use · Child Abuse and Neglect

Enrolled (actual)
47
Serious AEs
0.0%
Results posted
Feb 2014
Primary outcome: Primary: Maternal Capacity for Reflective Functioning (Assessed With the Parent Development Interview) — 3.59; 3.08; 3.54; 3.47 units on a scale

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Mentalizing Therapy for Substance Using Mothers (Behavioral); Standard Parent Education for Substance Using Mothers (Behavioral)
Age
Adult, Older Adult · 18+ yrs
Sex
Female
Sponsor
Yale University
Primary completion
Mar 2009

Outcome Measures

OutcomeResultp-value
PRIMARY
Maternal Capacity for Reflective Functioning (Assessed With the Parent Development Interview)
3.59; 3.08; 3.54; 3.47; 3.47; 3.09
PRIMARY
Quality of Maternal Representations of the Child (Assessed With the Working Model of the Child Interview)
2.86; 2.78; 2.86; 2.71
SECONDARY
Maternal Caregiving Behavior (Assessed With the NCAST Teaching Scales)
37.79; 35.75; 14.60; 13.01; 37.06; 34.61
SECONDARY
Child Behavior (Assessed With the NCAST Teaching Scales)
19.74; 18.78; 9.47; 9.16; 20.16; 18.66
SECONDARY
Maternal Depression (Measured With the Beck Depression Inventory)
13.57; 16.01; 14.37; 12.14
SECONDARY
Maternal Psychiatric Distress (Assessed With the Brief Symptom Inventory)
58.86; 60.24; 58.41; 58.29
SECONDARY
Maternal Substance Abuse (Assessed With Urine Toxicology Screens)
20; 22; 7; 6

Summary

The primary goal of this Stage I therapy development study will be to manualize and test the preliminary efficacy of a parenting intervention for drug dependent mothers that aims to foster their ability to recognize children's emotional needs at different ages and their capacity to be emotionally available to their children.

Eligibility Criteria

Inclusion Criteria

  • English-speaking adult women
  • history of primary alcohol, cocaine, cannabis, club drug, or heroin abuse or dependence
  • caring for a child between 1 and 36 months of age

Exclusion criteria

  • acute suicidality/ homicidality
  • severe psychiatric or substance-related symptoms requiring in-patient hospitalization or ambulatory detoxification
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00319436). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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