N/A
Completed N=44
Breathe: Slow Paced Breathing to Lower Blood Pressure
High Blood Pressure
Source: ClinicalTrials.gov NCT00328016 ↗
Enrolled (actual)
44
Serious AEs
0.0%
Results posted
Jul 2017
Primary outcomePrimary: Breathing Rate — 9.4; 13.7 Breaths/minute
Summary
The purpose of this study is to investigate the nature of the physiological reasons for the decreases in resting blood pressure that can result from systematic practice of computer-guided breathing exercises or meditative relaxation.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Breathing Rate |
9.4; 13.7 | — |
| SECONDARY Minute Ventilation |
7.6; 5.6 | — |
| SECONDARY End Tidal CO2 (PetCO2) |
30.1; 36.5 | — |
Eligibility Criteria
Inclusion Criteria
- Over 21 years
- Systolic blood pressure 130-160 or diastolic blood pressure 85-100
Exclusion Criteria
- More than one antihypertensive medication
- Beta blockers, angiotensin converting enzyme inhibitors or angiotensin receptor blockers
- History of coronary artery disease, heart failure, stroke, angina or coronary revascularization
- Kidney disease, defined as plasma creatinine > 1.5mg/dL
- Diabetes, defined by insulin or oral hypoglycemic medication or blood sugar > 126mg/dL
- Pulmonary disease, defined as chronic obstructive pulmonary disease, bronchitis, asthma, or use of inhaler
- Upper respiratory infection during past 30 days
- Medication that affects central nervous system function
- Steroid use
- Current pregnancy or lactation within past six months
- Current birth control medication or hormone replacement therapy
- Condition that in the judgment of the Principal Investigator is incompatible with the research study
Data sourced from ClinicalTrials.gov (NCT00328016). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.