N/A
N=44
Breathe: Slow Paced Breathing to Lower Blood Pressure
High Blood Pressure
Bottom Line
View on ClinicalTrials.gov: NCT00328016 ↗Enrolled (actual)
44
Serious AEs
0.0%
Results posted
Jul 2017
Primary outcome: Primary: Breathing Rate — 9.4; 13.7 Breaths/minute
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Guided Breathing (Behavioral); RESPeRATE (Device)
- Age
- Adult, Older Adult · 40+ yrs
- Sex
- All
- Sponsor
- National Institute on Aging (NIA)
- Primary completion
- Dec 2009
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Breathing Rate |
9.4; 13.7 | — |
| SECONDARY Minute Ventilation |
7.6; 5.6 | — |
| SECONDARY End Tidal CO2 (PetCO2) |
30.1; 36.5 | — |
Summary
The purpose of this study is to investigate the nature of the physiological reasons for the decreases in resting blood pressure that can result from systematic practice of computer-guided breathing exercises or meditative relaxation.
Eligibility Criteria
Inclusion Criteria
- Over 21 years
- Systolic blood pressure 130-160 or diastolic blood pressure 85-100
Exclusion Criteria
- More than one antihypertensive medication
- Beta blockers, angiotensin converting enzyme inhibitors or angiotensin receptor blockers
- History of coronary artery disease, heart failure, stroke, angina or coronary revascularization
- Kidney disease, defined as plasma creatinine > 1.5mg/dL
- Diabetes, defined by insulin or oral hypoglycemic medication or blood sugar > 126mg/dL
- Pulmonary disease, defined as chronic obstructive pulmonary disease, bronchitis, asthma, or use of inhaler
- Upper respiratory infection during past 30 days
- Medication that affects central nervous system function
- Steroid use
- Current pregnancy or lactation within past six months
- Current birth control medication or hormone replacement therapy
- Condition that in the judgment of the Principal Investigator is incompatible with the research study
Data sourced from ClinicalTrials.gov (NCT00328016). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.