Phase 3
N=211
Methadone Maintenance for Prisoners
Heroin Addiction
Bottom Line
View on ClinicalTrials.gov: NCT00378079 ↗Enrolled (actual)
211
Serious AEs
17.5%
Results posted
Apr 2014
Primary outcome: Primary: Treatment Retention in the Community — 23.1; 91.3; 166.0 Days in community treatment
Study Design & Population
- Study type
- Interventional
- Phase
- Phase 3
- Interventions
- Counseling Only (Other); Counseling + Transfer (Drug); Counseling + Methadone (Drug)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- Male
- Sponsor
- Friends Research Institute, Inc.
- Primary completion
- Jan 2008
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Treatment Retention in the Community |
23.1; 91.3; 166.0 | — |
| PRIMARY Heroin Use |
65.6; 48.7; 25.0 | — |
| PRIMARY Cocaine Use |
71.9; 66.6; 43.2 | — |
| PRIMARY HIV-risk Behaviors |
— | — |
| PRIMARY Criminal Activity |
106.7; 65.2; 81.8 | — |
| SECONDARY Employment |
12.0; 10.3; 8.5 | — |
Summary
This five-year study examines the benefits of methadone maintenance treatment initiated in prison and continued in the community to male offenders who were previously, but not currently, heroin-dependent. It is anticipated that such prisoners will have more favorable outcomes in the year following release with regard to drug abuse, crime, and HIV risk behavior than either prisoners who receive counseling only or begin initiation of methadone maintenance in the community
Eligibility Criteria
Inclusion Criteria
- Heroin dependence in the year prior to current incarceration
- 3-6 months left to serve in prison-male pre-release inmate suitability for methadone maintenance as determined by medical evaluation
- Willingness to enroll in methadone maintenance
- Having a Baltimore address
Exclusion Criteria
- Pending parole hearing
- Pending charges
- Kidney failure
- Liver failure
Data sourced from ClinicalTrials.gov (NCT00378079). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.