Phase 3
Completed N=211
Methadone Maintenance for Prisoners
Heroin Addiction
Source: ClinicalTrials.gov NCT00378079 ↗
Enrolled (actual)
211
Serious AEs
17.5%
Results posted
Apr 2014
Primary outcomePrimary: Treatment Retention in the Community — 23.1; 91.3; 166.0 Days in community treatment
Summary
This five-year study examines the benefits of methadone maintenance treatment initiated in prison and continued in the community to male offenders who were previously, but not currently, heroin-dependent. It is anticipated that such prisoners will have more favorable outcomes in the year following release with regard to drug abuse, crime, and HIV risk behavior than either prisoners who receive counseling only or begin initiation of methadone maintenance in the community
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Treatment Retention in the Community |
23.1; 91.3; 166.0 | — |
| PRIMARY Heroin Use |
65.6; 48.7; 25.0 | — |
| PRIMARY Cocaine Use |
71.9; 66.6; 43.2 | — |
| PRIMARY HIV-risk Behaviors |
— | — |
| PRIMARY Criminal Activity |
106.7; 65.2; 81.8 | — |
| SECONDARY Employment |
12.0; 10.3; 8.5 | — |
Eligibility Criteria
Inclusion Criteria
- Heroin dependence in the year prior to current incarceration
- 3-6 months left to serve in prison-male pre-release inmate suitability for methadone maintenance as determined by medical evaluation
- Willingness to enroll in methadone maintenance
- Having a Baltimore address
Exclusion Criteria
- Pending parole hearing
- Pending charges
- Kidney failure
- Liver failure
Data sourced from ClinicalTrials.gov (NCT00378079). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.