N/A
Completed N=1,099
Evaluating the Relationship Between Inflammation, Genetics, and Stress in the Development of High Blood Pressure
Source: ClinicalTrials.gov NCT00384241 ↗Enrolled (actual)
1,099
Serious AEs
0.0%
Results posted
Jun 2015
Primary outcomePrimary: Change in Urinary Sodium Excretion (UNaV) — 11.8; 15.2 pg/ml
Summary
High blood pressure affects nearly one third of all individuals in the United States. If left untreated, it can lead to stroke, heart failure, heart attack, kidney failure, or blindness. For many people, the exact cause of high blood pressure is unknown, but it is believed that both genetic and environmental factors contribute to the development of the condition. The purpose of this study is to examine the importance of genetics, inflammation, and stress on the development of high blood pressure.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in Urinary Sodium Excretion (UNaV) |
11.8; 15.2 | — |
| SECONDARY The Effect of Change in Stress Induced IL-6 on Systolic Blood Pressure |
108.9; 113.3 | — |
Eligibility Criteria
Inclusion Criteria
- Participated in two previous NIH funded studies HL073260, HL077230
- Biological parents willing to participate in the study
- African American or European origins
Exclusion Criteria
- Non-biological parents
Data sourced from ClinicalTrials.gov (NCT00384241). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.