Phase 2
Completed N=138
Fish Oil (Omega 3), Immune Function, and Mood
Source: ClinicalTrials.gov NCT00385723 ↗Enrolled (actual)
138
Serious AEs
0.0%
Results posted
Nov 2012
Primary outcomePrimary: Serum ln(TNF-a) — 0.66; 0.74; 0.71; 0.11 pg/ml (raw TNF-a) — p=0.03
Summary
This study is designed to examine the effects of fish oil on immune function and mood.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Serum ln(TNF-a) |
0.66; 0.74; 0.71; 0.11; 0.002; -0.024 | 0.03 sig |
| PRIMARY Serum ln(IL-6) |
0.91; 1.02; 0.85; 0.31; -0.106; -0.123 | 0.0003 sig |
| PRIMARY ln(CES-D) |
1.5; 1.5; 1.6; -0.056; -0.29; -0.26 | 0.80 |
Eligibility Criteria
Recruiting men and women ages 40-88 from the Greater Columbus Ohio area. Participation involves taking capsules for 4 months and completing 6 appointments (for a total of 19.5 hours) at Ohio State.
Inclusion Criteria
- Healthy men and women
- NOT currently taking any sort of fish oil or omega 3 supplement
Exclusion Criteria
- Use of blood pressure medicines, cholesterol-lowering drugs, steroids, or antidepressants
- Certain lifestyle habits such as smoking or exercising vigorously for 2 or more hours a week may also exclude applicants from participating
Data sourced from ClinicalTrials.gov (NCT00385723). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.