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Phase 4 N=20 Randomized Quadruple-blind Treatment

Effect of Nicotine on Chronic Pelvic Pain

Pelvic Pain

Enrolled (actual)
20
Serious AEs
0.0%
Results posted
Feb 2011
Primary outcome: Primary: Pain Score — 7.1; 6.4; 6.9 Units on a scale

Study Design & Population

Study type
Interventional
Phase
Phase 4
Interventions
Placebo (Drug); Nicotine (5 mg) (Drug); Nicotine (10 mg) (Drug)
Age
Adult · 18+ yrs
Sex
Female
Sponsor
Columbia University
Primary completion
Jun 2008

Outcome Measures

OutcomeResultp-value
PRIMARY
Pain Score
7.1; 6.4; 6.9
SECONDARY
Patient Self-assessment of Psychological Distress
40.2; 36.7; 37.5
SECONDARY
Number of Participants Who Reported an Increase in Daily Pain Medication Regime
2; 3; 2
SECONDARY
Nausea
2.3; 2.3; 2.3

Summary

The purpose of this study is to test whether transdermal nicotine reduces pain among women with chronic pelvic pain.

Eligibility Criteria

Inclusion Criteria

  • Chronic pelvic pain
  • Aged 18-60 years
  • Female

Exclusion Criteria

  • Uncontrolled hypertension
  • Cardiovascular disease
  • Current analgesic abuse
  • Pregnancy
  • Current usage of nicotine patch or gum
  • Allergy to adhesive tape
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00440505). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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