N/A
Completed N=102
Intravenous Versus Intravenous/Oral Antibiotics for Perforated Appendicitis
Perforated Appendicitis
Source: ClinicalTrials.gov NCT00462020 ↗
Enrolled (actual)
102
Serious AEs
0.0%
Results posted
Dec 2011
Primary outcomePrimary: Abscess After Appendectomy — 10; 10 number of patients
Summary
The objective of this study is to scientifically evaluate two different management strategies for perforated appendicitis.
The hypothesis is that early discharge with oral antibiotic therapy may result in a dramatic decrease in medical care expenses for the patient.
The primary outcome variable between the two strategies is abscess rate.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Abscess After Appendectomy |
10; 10 | — |
| SECONDARY Operative Time |
41.06; 46.30 | — |
| SECONDARY Time to Regular Diet |
68.00; 61.42 | — |
| SECONDARY Length of Stay After Operation |
6.06; 4.48 | — |
| SECONDARY Total Healthcare Visits |
3.1; 3.1 | — |
Eligibility Criteria
Inclusion Criteria
- Identifiable hole in the appendix or stool in the abdomen at the time of appendectomy
Exclusion Criteria
- Known immune deficiency
- Abscess identified on pre-op imaging
- Another condition affecting surgical decision making or recovery (e.g. hemophilia, severe cardiac or respiratory co-morbidities).
Data sourced from ClinicalTrials.gov (NCT00462020). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.