N/A N=27 Other

Effectiveness of Cranberry Ingestion on Bacterial Adhesion: An Adjunct Study

Asymptomatic Bacteriuria

Bottom Line

View on ClinicalTrials.gov: NCT00506025 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Jun 2010

Primary outcome: Primary: Antimicrobial Activity of Urine From Pregnant Subjects Following Cranberry Juice Cocktail (CJC) — 117.5; 105.0; 110.0 cfu per ml

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Cranberry Juice (Dietary_supplement); De-Activated Cranberry juice (Dietary_supplement)
Age: Adult · 18+ yrs
Sex: Female
Sponsor: University of California, Irvine
Primary completion: Feb 2008

Outcome Measures

Outcome	Result	p-value
PRIMARY Antimicrobial Activity of Urine From Pregnant Subjects Following Cranberry Juice Cocktail (CJC)	117.5; 105.0; 110.0	—

Summary

This study is to help determine if drinking cranberry juice can decrease risk for asymptomatic bacteriuria (ASB). ASB occurs when there are bacteria in the urine without any symptoms. It will also see if there is a difference in this effect between pregnant and non-pregnant women.This research project is also designed to see what happens to bacterial binding to the lining of the bladder after drinking cranberry juice when special problems occur with pregnancy such as diabetes (a sugar metabolism problem) or ASB is already occurring.

Eligibility Criteria

Inclusion Criteria

Intrauterine pregnancy
Documented fetal viability (either by fetal heart tones present by Doppler auscultation, or by ultrasonic visualization of cardiac motion
Estimated gestational age by last menstrual period and/or by ultrasonographic fetal measurements of 16 weeks or less

Exclusion Criteria

Exclusion criteria will include:
Suspected non-viable or ectopic gestation
Patient desires pregnancy termination
Significant underlying medical complication, such as chronic hypertension, insulin-requiring diabetes, chronic renal failure, cardiac disease, sickle cell disease, etc.
Maternal age less than 18 years
Patient is currently on or has received within the two weeks prior to enrollment antimicrobial therapy for reasons other than urinary tract infection.

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00506025). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.