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N/A N=22 Randomized Single-blind Treatment

Effect of a Novel Reamer-Irrigator-Aspirator on the Incidence of Fat Embolism

Embolism · Femoral Fractures

Enrolled (actual)
22
Serious AEs
18.2%
Results posted
May 2020
Primary outcome: Primary: Measurement of Embolic Debris — 5.3; 4.05 score on a scale

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Reamer Irrigator Aspirator (Device)
Age
Pediatric, Adult, Older Adult · 16+ yrs
Sex
All
Sponsor
Unity Health Toronto
Primary completion
Jan 2013

Outcome Measures

OutcomeResultp-value
PRIMARY
Measurement of Embolic Debris
5.3; 4.05

Summary

The purpose of this study is to determine the effect on the incidence of fat emboli when using a Reamer-Irrigator Aspirator during reamed IM nail fixation of femoral shaft fractures

Eligibility Criteria

Inclusion Criteria

  • Participant aged 16 to 65 years of age
  • Skeletally mature
  • Isolated, closed femoral shaft fracture (participant may also have sustained a distal radius/wrist, distal tibia/ankle, hand, and/or foot fractures for eligible inclusion)
  • Fracture amenable to an antegrade I.M. nail
  • Fracture amenable to insertion of a 12 mm RIA
  • Fracture ≤ 48 hrs post injury
  • Participant has a 'Thorax' Abbreviated Injury Score (AIS) of 48 hrs post injury
  • Limited life expectancy due to significant medical co-morbidities
  • Previous history of esophageal/gastric surgery
  • Previous history of esophageal/gastric tumor
  • Previous history of esophageal varices
  • Medical contraindication to surgery
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00509171). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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