N/A
N=146
Arthroscopy in the Treatment of Degenerative Medial Meniscus Tear
Osteoarthritis, Knee
Bottom Line
View on ClinicalTrials.gov: NCT00549172 ↗Enrolled (actual)
146
Serious AEs
0.7%
Results posted
Mar 2015
Primary outcome: Primary: The Lysholm Knee Score — 82.2; 83.4 units on a scale
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Operative (partial arthroscopy) (Procedure); Conservative (diagnostic arthroscopy) (Procedure)
- Age
- Adult, Older Adult · 35+ yrs
- Sex
- All
- Sponsor
- Tampere University
- Primary completion
- Mar 2013
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY The Lysholm Knee Score |
82.2; 83.4 | — |
| PRIMARY Pain After Exercise (VAS) |
2.7; 2.9 | — |
| PRIMARY WOMET (Western Ontario Meniscal Tear -Disease Specific Quality of Life -Assessment Tool) |
81.0; 79.9 | — |
| SECONDARY 15-D (General Quality of Life -Assessment Tool) |
0.94; 0.92 | — |
| SECONDARY Pain at Rest (VAS) |
1.6; 1.9 | — |
| SECONDARY Cost Effectiveness |
— | — |
Summary
Degenerative meniscal tears are the most common etiology for knee pain, swelling and loss of function. Partial arthroscopic meniscectomy is the most common orthopaedic procedure to treat meniscal tears. Improvements have been reported both after arthroscopy and with conservative treatment, however no direct comparison exist. Accordingly, the aim of this study is to assess the efficacy of arthroscopic partial meniscectomy for the treatment of degenerative tear of medial meniscus of the knee using a double-blind, placebo controlled, randomised trial.
Eligibility Criteria
Inclusion Criteria
- Age: 35 to 65 years of age.
- A pain located on the medial joint line of the knee that has persistent at least for 3 months.
- Pain that can be provoked by palpation or compression of the joint line or a positive McMurray sign.
- Tear of the medial meniscus on MRI.
- Degenerative rupture of the medial meniscus confirmed at arthroscopy.
Exclusion Criteria
- Acute, trauma-induced onset of symptoms.
- Locking or painful snapping of the knee joint.
- A surgical operation performed on the affected knee.
- Osteoarthritis of the medial compartment of the knee (determined by clinical criteria of the ACR).
- Osteoarthritis on knee radiographs (Kellgren-Lawrence > 1).
- Acute (within the previous year) fractures of the knee.
- Decreased range of motion of the knee.
- Instability of the knee.
- MRI assessment showing a tumor or any other complaint requiring surgical or other means of treatment.
- Arthroscopic assessment showing anything other than a degenerative tear of the medial meniscus requiring surgical intervention.
Data sourced from ClinicalTrials.gov (NCT00549172). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.