Phase 3 N=2,518 Randomized Prevention

Study of Bathing With Chlorhexidine Impregnated Cloths on Nosocomial Infections in the Pediatric Intensive Care Unit

Nosocomial Infections

Bottom Line

View on ClinicalTrials.gov: NCT00549393 ↗

Enrolled (actual)

2,518

Serious AEs

0.0%

Results posted

Oct 2015

Primary outcome: Primary: Bacteremia — 3.52; 4.93 events per 1000 at-risk days

Study Design & Population

Study type: Interventional
Phase: Phase 3
Interventions: 2% Chlorhexidine gluconate cloth (Drug)
Age: Pediatric, Adult · 0+ yrs
Sex: All
Sponsor: Johns Hopkins University
Primary completion: Dec 2010

Outcome Measures

Outcome	Result	p-value
PRIMARY Bacteremia	3.28; 4.93	—
SECONDARY Central Line Associated-bloodstream Infection (CLABSI)	1.63; 3.00	—

Summary

The investigators propose to conduct a large clinical study to determine if daily bathing with chlorhexidine impregnated cloths will reduce the incidence of healthcare-associated infections in the Pediatric Intensive Care Unit (PICU).

Eligibility Criteria

Inclusion Criteria

Patients in pediatric intensive care unit

Exclusion Criteria

Patients with a history of an allergic reaction to chlorhexidine
Patients less than 2 months of age
Patients with severe skin disease or burn
Patients with an indwelling epidural catheter or lumbar drain

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00549393). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.