N/A
Completed N=1,687
Hospital Design and Risk of Nosocomial Infections: A Prospective Controlled Trial
Vancomycin-resistant enterococci · Clostridium Difficile Infection · Nosocomial infection · Methicillin Resistant Staphylococcus Aureus Infection (MRSA)
Source: ClinicalTrials.gov NCT00563186 ↗
Enrolled (actual)
1,687
Serious AEs
0.0%
Results posted
Oct 2018
Primary outcomePrimary: Incidence Density of Hospital-acquired Infection With Clostridium Difficile (CDI), and Hospital-acquired Infection or Colonization With Vancomycin-resistant Enterococcus (VRE), or Methicillin-resistant Staphylococcus Aureus (MRSA). — 1.16; 0.84; 1.27; 1.01 events per 1000 patient days — p=0.18
Summary
With the construction of a new medical teaching ward with features designed to reduce hospital-acquired infections, we hypothesized that the design of the new ward was the major factor that contributed to the improved outcomes and designed a prospective, controlled study to examine this hypothesis.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Incidence Density of Hospital-acquired Infection With Clostridium Difficile (CDI), and Hospital-acquired Infection or Colonization With Vancomycin-resistant Enterococcus (VRE), or Methicillin-resistant Staphylococcus Aureus (MRSA). |
1.16; 0.84; 1.27; 1.01; 0.53; 0 | 0.18 |
| SECONDARY Number of MRSA, VRE and CDI Occurring in Single-bed Rooms vs. Multiple Bed Rooms AND Occurring in Outbreaks Related to the Primary Case |
3; 19 | — |
Eligibility Criteria
Inclusion Criteria
- are adults aged 18 or older with medical diagnoses being admitted to one of three in-hospital general medical services at the FMC (one of the two in-patient General Internal Medicine services at the FMC)
- are admitted via the emergency room
- are admitted from the urgent assessment clinic or the community
Exclusion Criteria
- are admitted from another acute care medical institution
- require telemetry monitoring of their cardiac rhythm (a specific medical situation that dictates need for admission to a nonUnit 36 bed).
- have other clinical circumstances (eg clinical instability) mandating a physician to indicate clinical preference for admission of the patient to a specific location in the hospital
- are admitted from the intensive care unit or another hospital ward
- are admitted for less than 48 hours
Data sourced from ClinicalTrials.gov (NCT00563186). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.