Mode
Text Size
Log in / Sign up
N/A N=1,687 Randomized Single-blind Prevention

Hospital Design and Risk of Nosocomial Infections: A Prospective Controlled Trial

Vancomycin Resistant Enterococci Infection · Clostridium Difficile Infection · Nosocomial Infection · Methicillin Resistant Staphylococcus Aureus Infection (MRSA)

Enrolled (actual)
1,687
Serious AEs
0.0%
Results posted
Oct 2018
Primary outcome: Primary: Incidence Density of Hospital-acquired Infection With Clostridium Difficile (CDI), and Hospital-acquired Infection or Colonization With Vancomycin-resistant Enterococcus (VRE), or Methicillin-resistant Staphylococcus Aureus (MRSA). — 1.16; 0.84; 1.27; 1.01 events per 1000 patient days — p=0.18

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Admission to a novel hospital ward (Other)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
University of Calgary
Primary completion
Feb 2010

Outcome Measures

OutcomeResultp-value
PRIMARY
Incidence Density of Hospital-acquired Infection With Clostridium Difficile (CDI), and Hospital-acquired Infection or Colonization With Vancomycin-resistant Enterococcus (VRE), or Methicillin-resistant Staphylococcus Aureus (MRSA).
1.16; 0.84; 1.27; 1.01; 0.53; 0 0.18
SECONDARY
Number of MRSA, VRE and CDI Occurring in Single-bed Rooms vs. Multiple Bed Rooms AND Occurring in Outbreaks Related to the Primary Case
3; 19

Summary

With the construction of a new medical teaching ward with features designed to reduce hospital-acquired infections, we hypothesized that the design of the new ward was the major factor that contributed to the improved outcomes and designed a prospective, controlled study to examine this hypothesis.

Eligibility Criteria

Inclusion Criteria

  • are adults aged 18 or older with medical diagnoses being admitted to one of three in-hospital general medical services at the FMC (one of the two in-patient General Internal Medicine services at the FMC)
  • are admitted via the emergency room
  • are admitted from the urgent assessment clinic or the community

Exclusion Criteria

  • are admitted from another acute care medical institution
  • require telemetry monitoring of their cardiac rhythm (a specific medical situation that dictates need for admission to a nonUnit 36 bed).
  • have other clinical circumstances (eg clinical instability) mandating a physician to indicate clinical preference for admission of the patient to a specific location in the hospital
  • are admitted from the intensive care unit or another hospital ward
  • are admitted for less than 48 hours
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00563186). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

Back to search