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Phase 3 N=890 Randomized Quadruple-blind Treatment

Safety Study of Olopatadine Nasal Spray

Perennial Allergic Rhinitis

Enrolled (actual)
890
Serious AEs
3.4%
Results posted
Feb 2010
Primary outcome: Primary: Mean Response at Day 30 to the Patient-rated Relief Assessment Questionnaire — 2.7; 2.5 Unit on PRRA scale

Study Design & Population

Study type
Interventional
Phase
Phase 3
Interventions
Olopatadine 0.6% nasal spray (Drug); Placebo Nasal Spray (Drug)
Age
Pediatric, Adult, Older Adult · 12+ yrs
Sex
All
Sponsor
Alcon Research
Primary completion
Jan 2008

Outcome Measures

OutcomeResultp-value
PRIMARY
Mean Response at Day 30 to the Patient-rated Relief Assessment Questionnaire
2.7; 2.5
SECONDARY
Average Number of Days of Rescue Medication Taken
10.2; 11.8

Summary

The purpose of this study is to determine whether olopatadine nasal spray is safe and effective when used for up to one year by patients with perennial allergic rhinitis.

Eligibility Criteria

Inclusion Criteria

  • Patients with confirmed diagnosis of perennial allergic rhinitis who are 12 years and older

Exclusion Criteria

  • Age 11 years and younger
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00578331). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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