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N/A Completed N=14 Randomized Single-blind Treatment

Evaluation of Orientation and Visual Acuity of Four Toric Soft Contact Lenses When Head is Tilted at 90 Degrees

Astigmatism
Source: ClinicalTrials.gov NCT00583908 ↗
Enrolled (actual)
14
Serious AEs
0.0%
Results posted
Sep 2009
Primary outcomePrimary: Lens Orientation During Head Tilt. — 12.2; 39.7; 27.6; 39.3 Degree of rotation — p=<0.0001

Summary

The purpose of this study is to determine the relative performance of a new toric soft contact lens against three toric contact lens currently available in market, specifically with orientation and visual acuity when head is tilted at 90 degrees.

Outcome Measures

OutcomeResultp-value
PRIMARY
Lens Orientation During Head Tilt.
12.2; 39.7; 27.6; 39.3 <0.0001 sig
PRIMARY
Visual Acuity During Head Tilt
0.02; 0.15; 0.07; 0.11 0.0083 sig
SECONDARY
Degree of Lens Rotation in Superior Gaze.
3.3; 6.0; 3.7; 6.5 0.16
SECONDARY
Degree of Lens Rotation in Superior-temporal Gaze.
6.3; 9.4; 4.9; 8.6 0.044 sig
SECONDARY
Degree of Lens Rotation in Superior-nasal Gaze.
6.2; 5.6; 6.9; 5.8 0.78
SECONDARY
Degree of Lens Rotation in Temporal Gaze.
4.1; 7.2; 2.8; 6.6 0.11
SECONDARY
Degree of Lens Rotation in Nasal Gaze.
3.2; 7.1; 2.4; 3.3 0.061
SECONDARY
Degree of Lens Rotation Inferior-temporal Gaze.
3.9; 5.3; 3.7; 2.5 0.17
SECONDARY
Degree of Lens Rotation in Inferior-nasal Gaze.
3.0; 9.0; 5.9; 9.5 0.0080 sig
SECONDARY
Degree of Lens Rotation in Inferior Gaze.
3.9; 5.0; 4.2; 2.4 0.27

Eligibility Criteria

Inclusion Criteria

  • be at least 18 and less than or equal to 50 years of age
  • be able and willing to adhere to the instructions set forth in the protocol.
  • have a distance spherical component between -1.00 D and -6.00D with cylinder in the range of 0.75 D to 1.75D
  • Sign the STATEMENT OF INFORMED CONSENT.
  • Have normal, healthy eyes

Exclusion Criteria

  • The presence of ocular or systemic disease or need for medication which might interfere with contact lens wear.
  • Pre-existing ocular disease precluding contact lens fitting.
  • Insufficient lacrimal secretions
  • Aphakia, keratoconus or a highly irregular cornea
  • Previous eye surgery involving the anterior segment
  • Current pregnancy or lactation (to the best of the subject's knowledge).
  • Use of concurrent ocular medication
  • Active participation in another clinical study at any time during this study.-
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00583908). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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