N/A
N=75
Family Based Contingency Management for Adolescent Alcohol Abuse
Alcohol Abuse
Bottom Line
View on ClinicalTrials.gov: NCT00595478 ↗Enrolled (actual)
75
Serious AEs
0.0%
Results posted
Mar 2018
Primary outcome: Primary: Alcohol Abstinence — 2.9; 2.6 Samples — p=0.66
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Motivational Enhancement Therapy (MET)/CBT+CM (Behavioral); Motivational Enhancement Therapy (MET)/CBT (Behavioral)
- Age
- Pediatric, Adult · 12+ yrs
- Sex
- All
- Sponsor
- Dartmouth-Hitchcock Medical Center
- Primary completion
- May 2014
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Alcohol Abstinence |
2.9; 2.6 | 0.66 |
| SECONDARY Days of Alcohol Use During 36-week Follow-up Period |
5.6; 7.6 | 0.74 |
Summary
The goal is to adapt the family-based CM treatment to target primary adolescent alcohol abuse and dependence.
Specific Aim 1 is to provide a preliminary demonstration of the efficacy of a family-based CM intervention to treat adolescent alcohol abuse and dependence. CM components include:
1. an incentive program to enhance the adolescent's engagement in the treatment process and engender alcohol abstinence by providing positive reinforcement for documented abstinence via breathalyzers administered by parents regularly at home, self and parent report, and clinic-based urine drug testing; and
2. a parent management training program to enhance and maintain the positive effects of the incentive program by teaching parents how to effectively use contingency management in the home environment to motivate their adolescent to achieve abstinence and improve their behavior in other domains.
A randomized trial will determine whether the CM intervention enhances outcomes when added to a standard individual cognitive behavioral therapy (CBT).
Specific Aim 2 is to determine whether and how treatment interventions modify parental and adolescent risk and protective factors using observational and laboratory measures (parenting practices, family functioning, risk taking, delay discounting, and child and parent psychopathology) and to determine whether these factors are associated with outcomes over time.
Specific Aim 3 is to test gene x environment (treatment) interactions in adolescent substance abuse. Findings will extend the scientific evidence for CM and support the ability of parents to implement CM at home. Findings that support the CM model's efficacy will make a significant contribution to research on the treatment of adolescent alcohol abuse, which has lagged behind research on adult substance abuse and on adolescent illicit drug use.
Eligibility Criteria
Inclusion Criteria
- 12-18 years old (if 18, must attend high school and live at home)
- Report using alcohol during the previous 30 days
- Have a parent/guardian who can participate
- Meet DSM criteria for either Alcohol Abuse or Dependence
- Youth who meet DSM criteria for Alcohol Dependence may also meet criteria for Marijuana Abuse or Dependence and other Drug Abuse
- Youth who meet DSM criteria for Alcohol Abuse, may also meet criteria for Marijuana or other Drug Abuse
- Live within a 30-minute drive of the clinic
Exclusion Criteria
- Meet DSM criteria for Drug Dependence (other than Marijuana Dependence)
- Meet DSM criteria for Alcohol Abuse with Marijuana Dependence. Use of other drugs will not be excluded
- Participants will also be excluded if they exhibit an active psychosis
- Have a severe medical or psychiatric illness that will limit participation
- Are pregnant or breast-feeding
Data sourced from ClinicalTrials.gov (NCT00595478). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.