N/A
Completed N=87
Stress and Marijuana Cue-elicited Craving and Reactivity
Cannabis Use Disorders
Source: ClinicalTrials.gov NCT00613405 ↗
Enrolled (actual)
87
Serious AEs
0.0%
Results posted
May 2012
Primary outcomePrimary: Subjective Craving of Marijuana — 50.5; 52.3 Scores on a Scale
Summary
The purpose of this study is to explore the interaction between stress and marijuana cues, in hopes that it may lead to the development of new treatments for marijuana dependence.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Subjective Craving of Marijuana |
50.5; 52.3 | — |
| SECONDARY Physiological Assessments: Serum Cortisol, ACTH, BP, HR, and GSR |
— | — |
| SECONDARY Feelings of Stress/Anxiety as Measured by the State-Trait Inventory (STAI) |
— | — |
| SECONDARY Current Mood as Assessed by the Mood Form |
— | — |
Eligibility Criteria
Inclusion Criteria
- Meets Diagnostic and Statistical Methods (DSM)-IV Criteria for Marijuana Dependence
- Between the ages of 18 and 65
- Must abstain from marijuana use the day of testing and other drug use three days prior to testing
Exclusion Criteria
- Must not be taking any psychoactive medication, or medication that alters the hypothalamic pituitary adrenal (HPA) Axis functioning
- Must not be taking any medications that alter heart rate or skin conductance monitoring
- Cannot meet criteria for current major Axis I disorder (may alter response to stress)
- Cannot be morbidly obese (Body Mass Index >39)
- Cannot meet current abuse or dependence criteria of other substances in past 90 days
- Must not have a medical condition that impacts HPA functioning (Hypertension, chronic pain, Addison's disease)
Data sourced from ClinicalTrials.gov (NCT00613405). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.