N/A N=22 Randomized Prevention

Calcium Retention as Influenced by Dietary Components That Induce an Acid Load

Healthy

Bottom Line

View on ClinicalTrials.gov: NCT00620763 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Aug 2009

Primary outcome: Primary: Calcium Absorption — 30.4; 25.4 percentage of Calcium-47 absorbed — p=0.02

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: High Meat - High Potential Renal Acid Load (PRAL) diet (Other); Low Protein - Low Potential Renal Acid Load (PRAL) diet (Other)
Age: Adult, Older Adult · 40+ yrs
Sex: Female
Sponsor: USDA Grand Forks Human Nutrition Research Center
Primary completion: May 2008

Outcome Measures

Outcome	Result	p-value
PRIMARY Calcium Absorption	30.4; 25.4	0.02 sig

Summary

The impact of protein sources such as beef as part of Western diet on calcium retention remains controversial. We propose to test the hypothesis that the positive effect of high protein intake (especially from meat protein) can offset the negative effect of protein-induced net acid load on bone metabolism and the retention of body calcium. Healthy postmenopausal women recruited from the community will consume two diets differing in meat protein and acid load for 7 weeks. Calcium retention from diets will be determined using a highly sensitive measurement of whole body retention of a calcium isotope added to the diet.

Eligibility Criteria

Inclusion Criteria

Average body mass index
Normal blood work
Normal bone density

Exclusion Criteria

Chronic disorder
Non-traumatic bone fractures

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00620763). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.