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Phase 2 N=51 Randomized Quadruple-blind Treatment

Ziprasidone in the Psychosis Prodrome

Psychosis Prodrome

Enrolled (actual)
51
Serious AEs
0.0%
Results posted
Oct 2016
Primary outcome: Primary: Conversion to Psychosis — 1; 2 participants

Study Design & Population

Study type
Interventional
Phase
Phase 2
Interventions
ziprasidone (Drug); placebo (Drug)
Age
Pediatric, Adult · 16+ yrs
Sex
All
Sponsor
Yale University
Primary completion
Nov 2012

Outcome Measures

OutcomeResultp-value
PRIMARY
Conversion to Psychosis
1; 2
SECONDARY
Change in Scale of Psychosis-risk Symptoms Total Score
-0.271; 0

Summary

This study aims to determine whether ziprasidone is superior to placebo over 24 weeks for patients with the psychosis prodrome.

Eligibility Criteria

Inclusion Criteria

  • Structured Interview for Psychosis-risk Syndromes criteria for Clinical High Risk for Psychosis
  • clinically referred

Exclusion Criteria

  • prolonged corrected QT interval
  • history of syncope
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00635700). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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