N/A N=80 Randomized Triple-blind Treatment

Effect of Whey Protein Supplementation and Resistance Exercise on Muscle Parameters in Older Adults

Mobility Limitation

Bottom Line

View on ClinicalTrials.gov: NCT00635739 ↗

Enrolled (actual)

Serious AEs

11.3%

Results posted

Mar 2019

Primary outcome: Primary: 1 Repetition Maximum Muscle Strength 1-RM (N) Double Leg Press — 1223; 1256; 1483; 1465 N

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Whey protein (Dietary_supplement); Maltodextrin placebo (Dietary_supplement)
Age: Older Adult · 70+ yrs
Sex: All
Sponsor: Tufts University
Primary completion: May 2011

Outcome Measures

Outcome	Result	p-value
PRIMARY 1 Repetition Maximum Muscle Strength 1-RM (N) Double Leg Press	1223; 1256; 1483; 1465	—
SECONDARY Lean Mass	46.7; 46.4; 47.3; 46.7	—

Summary

This research study is looking at the effects of a whey protein nutritional supplement on changes in muscle mass, strength and physical function in response to a 6 month program of strength training exercise.

Eligibility Criteria

Inclusion Criteria

Male and Females 70-85 yrs
Community dwelling
Short Physical Performance Battery score 150/90 mm Hg).
Neuromuscular diseases and drugs which affect neuromuscular function.
Hormone replacement therapy
eGFR <30 mL/min/1.73m2
Types I and II Diabetes Mellitus
Dietary protein intake < 0.8 g.kg-1.day-1
Disorders of nutrient absorption
Milk, or whey allergy
Sulfa drugs and allergy to PABA-containing sunscreens

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00635739). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.