N/A
N=65
The Effect of Sedation on Eye Movements
Saccadic Eye Movements
Bottom Line
View on ClinicalTrials.gov: NCT00646646 ↗Enrolled (actual)
65
Serious AEs
0.0%
Results posted
May 2014
Primary outcome: Primary: Dynamic Eye Movement Measures — -25; -115; -90; 10 (degrees/second)
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- propofol (Drug); dexmedetomidine (Drug); Midazolam (Drug); saline placebo (Drug)
- Age
- Adult, Older Adult · 19+ yrs
- Sex
- All
- Sponsor
- University of Alabama at Birmingham
- Primary completion
- Oct 2008
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Dynamic Eye Movement Measures |
-25; -115; -90; 10 | — |
Summary
The purpose of this study is to determine whether sedation affects saccadic eye movements.
Eligibility Criteria
Inclusion Criteria
- Healthy, human volunteers, age 19-65.
- American Society of Anesthesiology (ASA) class I-II for inclusion criteria
Exclusion Criteria
- Pregnancy
- Respiratory disease (severe asthma, emphysema)
- Cardiac disease (coronary artery disease, congestive heart failure)
- Symptomatic reflux disease
- Advanced rheumatic disease involving cervical spine
- Propofol or egg allergy
- Neurological disease (stroke, intracranial processes)
- Severe anemia
Data sourced from ClinicalTrials.gov (NCT00646646). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.