Phase 4
Completed N=106
Veteran Stress and Learning Study
Stress Disorders, Posttraumatic
Source: ClinicalTrials.gov NCT00674570 ↗
Enrolled (actual)
106
Serious AEs
0.0%
Results posted
May 2019
Primary outcomePrimary: Proportion of Maximum Skin Conductance Response (SCR) in Microsiemens (µS) — .0325522; .0245775; -.0181339; .1233174 proportion of max SCR (µS) — p==.66
◆ Published Evidence
Established
▲ Trending
21citations · ~5 / year
Early pharmacological interventions for universal prevention of post-traumatic stress disorder (PTSD).
Summary
This is a research study examining the use of two medications, Hydrocortisone and D-Cycloserine, compared to an inactive substance (placebo), on their ability to reduce fear responses and memory of fear in Veterans with symptoms of Posttraumatic Stress Disorder (PTSD). These responses will be tested using a fear learning and memory task administered by computer.
Linked Publications (2)
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Early pharmacological interventions for universal prevention of post-traumatic stress disorder (PTSD).
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Early pharmacological interventions for prevention of post-traumatic stress disorder (PTSD) in individuals experiencing acute traumatic stress symptoms.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Proportion of Maximum Skin Conductance Response (SCR) in Microsiemens (µS) |
.0325522; .0245775; -.0181339; .1233174; .1024914; .1276977 | =.66 |
Eligibility Criteria
Inclusion Criteria
- Veterans and civilians with an age range of 18 to 65 years
- Participants must be physically healthy volunteers
Exclusion Criteria
- Individuals who fall outside the age range
- Individuals with medical conditions that would interfere with participation
- Other criteria
Data sourced from ClinicalTrials.gov (NCT00674570) and the linked publication. Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.