Phase 3
Completed N=83
Neuromuscular Electrical Stimulation in Chronic Obstructive Pulmonary Disease (COPD)
Source: ClinicalTrials.gov NCT00677690 ↗Enrolled (actual)
83
Serious AEs
—
Results posted
Apr 2009
Primary outcomePrimary: Exercise Capacity — 465.5; 462.7 meters — p=<0.05
Summary
The purpose of this study is to elucidate whether combination of usual pulmonary rehabilitation and neuromuscular electrical stimulation of quadriceps may improve exercise capacity in patients affected by chronic obstructive pulmonary disease (COPD).
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Exercise Capacity |
465.5; 462.7 | <0.05 sig |
| PRIMARY Quadriceps Strength |
13.5; 13.6 | <0.05 sig |
| SECONDARY Dyspnoea |
2.4; 2.6 | < 0.05 sig |
| SECONDARY Quality of Life |
41.7; 42.05 | <0.05 sig |
| SECONDARY Respiratory Function |
50.1; 49.6 | <0.05 sig |
Eligibility Criteria
Inclusion Criteria
- Clinical diagnosis of COPD
- Must be able to walk
Exclusion Criteria
- Previous or current diagnosis of chronic respiratory failure
- A history of diseases other than COPD, in particular neurological disease
- Need for treatment with systemic steroids during the rehabilitation period
Data sourced from ClinicalTrials.gov (NCT00677690). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.