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Phase 3 N=168 Randomized Prevention

Closed Suction Drainage and Natural Drainage of the Pancreatic Duct in Pancreaticojejunostomy

Pancreatic Fistula

Enrolled (actual)
168
Serious AEs
0.0%
Results posted
May 2011
Primary outcome: Primary: Number of Patients With Pancreatic Fistula — 9; 8 participants

Study Design & Population

Study type
Interventional
Phase
Phase 3
Interventions
closed suction drainage of pancreatic duct (Procedure); natural drainage of pancreatic duct (Procedure)
Age
Pediatric, Adult, Older Adult · 15+ yrs
Sex
All
Sponsor
Seoul National University Hospital
Primary completion
Mar 2009

Outcome Measures

OutcomeResultp-value
PRIMARY
Number of Patients With Pancreatic Fistula
9; 8
SECONDARY
Severity of Pancreatic Fistulas

Summary

Pancreaticojejunal anastomosis leakage is a major complication after pancreatoduodenectomy and various technical methods have been examined to improve the situation.However, none of methods have been successful at improving results according to the findings of prospective randomized studies. We propose that active drainage of pancreatic juice using suction drainage might maximize the advantage of a stent and finally reduce pancreaticojejunal anastomosis leakage.

Eligibility Criteria

Inclusion Criteria

  • All patients who undergo duct-to-mucosa pancreaticojejunostomy reconstruction after pancreatoduodenectomy in our institution

Exclusion criteria

  • less than 15 years old, or older than 85 years old
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00679952). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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