N/A
Completed N=16
Tear Film Break-up Time After Instillation of Artificial Tears
Keratoconjunctivitis Sicca
Source: ClinicalTrials.gov NCT00681265 ↗
Enrolled (actual)
16
Serious AEs
0.0%
Results posted
Oct 2012
Primary outcomePrimary: Noninvasive Tear Film Break-up Time — 14.67; 7.4 seconds
Summary
This study is an exploratory trial evaluating the tear film break-up time after a single eye drop instillation of over-the-counter artificial tears. The primary hypothesis is that tear film break up time will be greater for test than control eye.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Noninvasive Tear Film Break-up Time |
14.67; 7.4 | — |
| SECONDARY Fluorescein Tear Film Break-up Time |
11.13; 6.21 | — |
Eligibility Criteria
Inclusion Criteria
- Age > 18 years
- symptoms of dry eye
- no other history of ophthalmic problems
Exclusion Criteria
- Use of any ocular lubricant or ointment in the past 36 hours
- use of contact lenses or excessive eye lid cosmetics on the study day
Data sourced from ClinicalTrials.gov (NCT00681265). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.