Phase 3
N=349
Metoclopramide for Migraine: A Dose Finding Study
Migraine
Bottom Line
View on ClinicalTrials.gov: NCT00682734 ↗Enrolled (actual)
349
Serious AEs
0.3%
Results posted
Dec 2012
Primary outcome: Primary: Pain Intensity Score — 4.7; 4.9; 5.3 scores on a scale
Study Design & Population
- Study type
- Interventional
- Phase
- Phase 3
- Interventions
- metoclopramide (Drug); Diphenhydramine 25mg (Drug)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Montefiore Medical Center
- Primary completion
- Mar 2010
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Pain Intensity Score |
4.7; 4.9; 5.3 | — |
Summary
Metoclopramide is an effective intravenous treatment for acute migraine attacks, but we do not know the best dose to administer. This study compares three different doses of metoclorpamide.
Eligibility Criteria
Inclusion Criteria
- acute migraine
Exclusion Criteria
- secondary cause of headache
- lumbar puncture
- allergy or intolerance to study medication
Data sourced from ClinicalTrials.gov (NCT00682734). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.