Phase 4
N=59
Prevention of Contrast-Induced Nephropathy With Sodium Bicarbonate Bolus Injection
Emergent Coronary Procedure
Bottom Line
View on ClinicalTrials.gov: NCT00700375 ↗Enrolled (actual)
59
Serious AEs
8.5%
Results posted
Jul 2010
Primary outcome: Primary: Occurrence of Contrast-induced Nephropathy — 1; 8 participants
Study Design & Population
- Study type
- Interventional
- Phase
- Phase 4
- Interventions
- Sodium bicarbonate (Drug); Sodium Chloride (Drug)
- Age
- Adult, Older Adult · 20+ yrs
- Sex
- All
- Sponsor
- Osaka General Medical Center
- Primary completion
- Mar 2010
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Occurrence of Contrast-induced Nephropathy |
1; 8 | — |
Summary
This study is to investigate the effect of Sodium Bicarbonate bolus injection in patients undergoing an emergent coronary procedure for prevention of contrast-induced nephropathy.
Eligibility Criteria
Inclusion Criteria
- Patients undergoing an emergent coronary procedure(within 60 minutes from admission)
Exclusion Criteria
- On dialysis
- Pregnancy
- Past use of bicarbonate or N-Acetyl-Cystein in 48hr
- Past exposure to contrast media in 48hr
- Circulatory insufficiency with lactic acidosis.
Data sourced from ClinicalTrials.gov (NCT00700375). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.