N/A
Completed N=12
NB-UVB Phototherapy With and Without Topical LCD Treatment: a Bilateral Pilot Study
Source: ClinicalTrials.gov NCT00708851 ↗Enrolled (actual)
12
Serious AEs
0.0%
Results posted
Apr 2015
Primary outcomePrimary: The Difference in Bilateral Static Physician's Global Assessment (sPGA) Scores, and Erythema, Scaling, and Induration (ESI) Scores of Bilateral Target Lesion Scores Across Visits for Each Condition and Between Conditions. — 77.8; 85.4; 88.5; 88.9 percent improvement from baseline
Summary
The purpose of this study is to determine if combining a daily at-home regimen using an LCD Solution with a 3 times weekly outpatient narrowband UVB phototherapy regimen could be a safe, effective, rapid, and, convenient treatment for plaque psoriasis.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY The Difference in Bilateral Static Physician's Global Assessment (sPGA) Scores, and Erythema, Scaling, and Induration (ESI) Scores of Bilateral Target Lesion Scores Across Visits for Each Condition and Between Conditions. |
77.8; 85.4; 88.5; 88.9; 84.2; 85.7 | — |
| SECONDARY The Difference in Number and Severity of Treatment-related Adverse Reactions Between Conditions. |
3; 3 | — |
Eligibility Criteria
Inclusion Criteria
- 18 years old or older
- able and willing to provide written informed consent
- symmetrical plaque psoriasis
- able and willing to attend phototherapy sessions and apply LCD at home
- negative pregnancy test for women of child-bearing potential
Exclusion Criteria
- current or recent other treatments for psoriasis
- hypersensitivity to LCD or UVB light
- current or previous skin cancer
- pregnant or nursing mother
- participating in another clinical trial
Data sourced from ClinicalTrials.gov (NCT00708851). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.