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Phase 4 N=33 Randomized Double-blind Other

A Two-week Crossover Evaluation of Two Hand Antiseptic Products on Skin Condition in Healthy Human Subjects

Healthy

Enrolled (actual)
33
Serious AEs
0.0%
Results posted
Jun 2009
Primary outcome: Primary: Change From Baseline in Skin Health, Visual Skin Score (VSS) at 14 Days — 0.1; 0.4 units on a scale

Study Design & Population

Study type
Interventional
Phase
Phase 4
Interventions
Avagard (Drug); Purell Surgical Scrub (Drug)
Age
Adult · 25+ yrs
Sex
Female
Sponsor
Solventum US LLC
Primary completion
Apr 2008

Outcome Measures

OutcomeResultp-value
PRIMARY
Change From Baseline in Skin Health, Visual Skin Score (VSS) at 14 Days
0.1; 0.4

Summary

Evaluate the effect of two hand antiseptic products on hand skin conditions of healthy volunteers.

Eligibility Criteria

Inclusion Criteria

  • Female age 25 - 55
  • Subject agrees not to use any hand wash products on their hands other than what has been provided in the study.
  • Subject agrees not to use any moisturizers or any skin products on their hands during the study
  • Subject agrees to use gloves to protect hands from activities such as dish washing
  • Subject is willing to sign the Informed Consent and HIPAA
  • Subject agrees to comply with the study requirement

Exclusion Criteria

  • Subject has a history of psoriasis, active dermatitis, skin reactions, cracked, irritated, broken skin, skin infection on their hands
  • Subject has scaly skin on hands based on Visual Scoring Scale at Day 1
  • Subject has a sensitivity or history of skin reactions to any study materials (eg, alcohol, chlorhexidine gluconate or zinc pyrithone or latex in the gloves)
  • Subject has been using moisturizing products or any products on their arms and hands within 5 days prior to participation in the study
  • Subject is pregnant
  • Study coordinator believes the subject is unsuitable for inclusion in the study
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00731042). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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