Phase 4
Completed N=153
Does Treatment With Macrobid Reduce Urinary Tract Infections in Patients Receiving a Sub-Urethral Sling for Incontinence
Stress Incontinence
Source: ClinicalTrials.gov NCT00734968 ↗
Enrolled (actual)
153
Serious AEs
0.0%
Results posted
Oct 2016
Primary outcomePrimary: Incidence of Post-operative UTI Following the Placement of Sub-urethral Sling for the Treatment of Stress Urinary Incontinence — 13; 24 participants
◆ Published Evidence
Established
35citations · ~3 / year
Antibiotic prophylaxis for urinary tract infection after midurethral sling: a randomized controlled trial.
Summary
This project will determine whether post-operative prophylaxis with macrobid will decrease the incidence of postoperative urinary tract infection in women receiving sub-urethral slings for the treatment of urinary incontinence.
Linked Publications (2)
-
Antibiotic prophylaxis for urinary tract infection after midurethral sling: a randomized controlled trial.
-
Prophylactic antibiotics for preventing infection after continence surgery in women with stress urinary incontinence.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Incidence of Post-operative UTI Following the Placement of Sub-urethral Sling for the Treatment of Stress Urinary Incontinence |
13; 24 | — |
| PRIMARY Incidence of Post-operative UTI in Placebo Group |
13; 24 | — |
| PRIMARY Incidence of Post-operative UTI in Treatment Group |
13; 24 | — |
Eligibility Criteria
Inclusion Criteria
- Women over the age of 18 who will undergo the placement of a sub-urethral sling for the treatment of stress urinary incontinence
Exclusion Criteria
- Exclusion criteria are those with a known allergy to macrobid, those with glucose-6-phosphate deficiency, renal impairment, women breast feeding or with a known pregnancy, patients taking medications for gout, and those with known risk factors for complicated UTI (polycystic renal disease, nephrolithiasis, neurogenic bladder, diabetes, immuno-suppression, etc).
Data sourced from ClinicalTrials.gov (NCT00734968) and the linked publication. Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.