Phase 3
N=48
Povidone-iodine Against Sodium Hypochlorite as Skin Antiseptics
Healthy Volunteers
Bottom Line
View on ClinicalTrials.gov: NCT00738543 ↗Enrolled (actual)
48
Serious AEs
0.0%
Results posted
Aug 2010
Primary outcome: Primary: Bacterial Count of Skin Cultures for the 10% Povidone-iodine Period — 231 Colony-forming units per cm squared — p=<0.05
Study Design & Population
- Study type
- Interventional
- Phase
- Phase 3
- Interventions
- WHOLE GROUP OF 48 VOLUNTEERS (Other)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Universidad de Guanajuato
- Primary completion
- Dec 2008
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Bacterial Count of Skin Cultures for the 10% Povidone-iodine Period |
231 | <0.05 sig |
| PRIMARY Bacterial Colony Forming Units for the 10% Sodium Hypochlorite Period |
192 | <0.05 sig |
| PRIMARY Bacterial Colony Forming Units for the Control Period |
1500 | — |
| SECONDARY Presence of Skin Reactions for the 10% Povidone-iodine Period |
— | — |
| SECONDARY Presence af Allergy or Skin Reaction for the 10% Sodium Hypochlorite Period |
— | — |
Summary
The investigators have few options for skin antisepsis. Alternatives for povidone-iodine, which is the most commonly used agent, are costly or ineffective. To have more options, this study is needed. The investigators want to know if there are difference between the use of 10% sodium hypochlorite or 10% povidone-iodine for skin antisepsis.
Eligibility Criteria
Inclusion Criteria
- Healthy adult volunteers.
Exclusion Criteria
- History of skin allergies or atopy, as well as reactions to soaps, iodine, chlorine, or latex
Data sourced from ClinicalTrials.gov (NCT00738543). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.